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Cincinnati Children's Hospital Medical Center

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Universal Ebola vaccine shows promise in pre-clinical trials

17 April 2020 | By Victoria Rees (Drug Target Review)

An Ebola vaccine that has been tested in animals could potentially be used to neutralise four species of the virus, say the researchers.

news

New study could lead to better treatments for autoimmune diseases

18 December 2019 | By Rachael Harper (Drug Target Review)

A study has found a new molecular process in mice that causes autoimmune diseases and has opened avenues for developing more effective autoimmune therapies.

news

Protein vital for T cell formation and function revealed

29 October 2019 | By Victoria Rees (Drug Target Review)

Researchers have discovered a protein that is required for T cell biological processes; they have also demonstrated the mechanism behind the protein.

news

Drug target discovered for pulmonary arterial hypertension

13 September 2019 | By Rachael Harper (Drug Target Review)

Scientists have discovered a molecular pathway that contributes to PAH development, which may lead to a new drug target for the disease.

news

Timing could be crucial when taking medication

14 September 2018 | By Iqra Farooq (Drug Target Review)

Researchers used a bioinformatic tool to suggest that circadian timing could be key to the success of certain drugs or therapies...

news

Blocking RNA-silencing protein Ago2 shows promise for obesity prevention

12 September 2018 | By Drug Target Review

Researchers are hopeful of finding a means to inhibit obesity and its associated health problems after a study in which they blocked an RNA-silencing protein in the livers of mice, preventing obesity and diabetic conditions.

news

EBV protein can ‘switch on’ risk genes for autoimmune diseases

17 April 2018 | By Drug Target Review

EBV may trigger some cases of lupus, say NIH-supported researchers...

news

Molecular therapy restores nerve insulation on peripheral nerves

13 February 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have described an experimental molecular therapy that restores insulation on peripheral nerves in mice, improves limb function, and results in less observable discomfort...

news

Gimap5 gene mutations found to trigger immune diseases

30 January 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists discovered how a gene mutation affects T cell function to promote immune disorders...

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Cincinnati Children's Hospital Medical Center