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Children's National Hospital

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Signalling pathway identified as target against paediatric glioma

25 August 2021 | By Anna Begley (Drug Target Review)

Researchers have found a vulnerability in a developmental signalling pathway, presenting a target for paediatric low-grade glioma formation.

news

New mouse model could be used to develop better HIV treatments

17 May 2021 | By Victoria Rees (Drug Target Review)

A new pre-clinical mouse model could enable the study of HIV infection and the testing of cell therapies against the virus.

news

Tumour cell vaccine strategy developed for neuroblastoma and melanoma

1 April 2021 | By Victoria Rees (Drug Target Review)

A combination of checkpoint and small molecule inhibitors showed success at targeting Myc oncogenes in mouse neuroblastoma and melanoma models.

news

Experimental mouse model of Duchenne muscular dystrophy developed

2 April 2020 | By Victoria Rees (Drug Target Review)

Researchers have created an accurate mouse model of Duchenne muscular dystrophy (DMD), showing that TGFβ is a potential target for the condition.

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Children's National Hospital

Signalling pathway identified as target against paediatric glioma

New mouse model could be used to develop better HIV treatments

Tumour cell vaccine strategy developed for neuroblastoma and melanoma

Experimental mouse model of Duchenne muscular dystrophy developed