news Blueprint Medicines to develop novel therapeutics targeting immunokinases 15 March 2016 | By Victoria White Under a collaboration with Roche, Blueprint Medicines will lead preclinical research and development through to Phase I proof of concept...
news FDA grants orphan drug designation to BLU-554 30 September 2015 | By Victoria White BLU-554, an exquisitely selective inhibitor of fibroblast growth factor receptor 4 (FGFR4), is currently being evaluated in a Phase 1 clinical trial in patients with advanced hepatocellular carcinoma...
news Blueprint Medicines to advance BLU-285 in Phase 1 trial for systemic mastocytosis 10 September 2015 | By Victoria White BLU-285 is a potent and highly selective inhibitor of the KIT D816V mutant, the primary driver of disease in more than 94% of systemic mastocytosis patients...
news Blueprint Medicines announces first preclinical data for BLU6864 23 June 2015 | By Victoria White Blueprint Medicines has announced the first preclinical data for its drug candidate BLU6864, a RET-specific kinase inhibitor.
news Preclinical data demonstrates BLU-554 induces significant tumour regression in models of hepatocellular carcinoma 24 April 2015 | By Victoria White New preclinical data demonstrates that BLU-554 has significant anti-tumour activity in models of HCC that are dependent on FGFR4 signalling...
news Blueprint Medicines presents preclinical data demonstrating significant anti-tumour activity of BLU-285 in treatment-resistant GIST 20 April 2015 | By Victoria White New preclinical data demonstrates that BLU-285 has significant anti-tumour activity in treatment-resistant models of gastrointestinal stromal tumours (GIST)...