BellBrook Labs

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Guide: Navigating hit prioritisation using biochemical assays

7 September 2020 | By BellBrook Labs

So you have performed your screen. What’s next? This guide is focused on how biochemical assays are used for characterising and prioritising compounds.

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BellBrook Labs

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Expert view: Targeting the cGAS-STING pathway with a new Transcreener HTS assay

24 March 2020 | By BellBrook Labs

DNA in the cytoplasm is an indicator of microbial infection, serving as a danger signal and resulting in induction of an innate immune response via the cyclic GAMP synthase (cGAS)/STING (Stimulator of INterferon-sensitive Genes) pathway.

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BellBrook Labs

Guide: Navigating hit prioritisation using biochemical assays

BellBrook Labs

Expert view: Targeting the cGAS-STING pathway with a new Transcreener HTS assay