Manipulation of primary cilia shows promise in osteoarthritis 28 October 2015 | By Victoria White Scientists have demonstrated that medical manipulation of the primary cilia disrupts a key biological process called 'Hedgehog Signalling'...
SRI International awarded $40m to develop contraceptive products 28 October 2015 | By Victoria White Under the contract, SRI International will conduct all research and testing necessary to submit Investigational New Drug applications for promising drugs...
XBiotech to develop antibody against C. Difficile 27 October 2015 | By Victoria White Using its proprietary True Human technology, the Company has begun screening human blood samples from donors to identify and clone a therapeutic antibody candidate...
Scientists discover a switch associated with epileptic seizures 27 October 2015 | By Victoria White If the researchers blocked a central switch in epileptic mice, the frequency and severity of the seizures decreased...
Scientists build protein cage cancer drug delivery system 27 October 2015 | By Victoria White Testing the system with lung cancer cells, the researchers showed that the ligand-guided protein cages selectively penetrated and killed more than 70% of the cancer cells...
Ipsen and EpiVax produce next generation botulinum toxins 27 October 2015 | By Victoria White Their "stealth" botulinum neurotoxin programme capitalises on technological advances and promises to bring better drugs, with defined mechanisms of action...
Scientists discover switched off gene in prostate cancer cells 26 October 2015 | By Victoria White The discovery could shed light on how prostate cancer spreads and provides a possible new target for the disease...
Chemical probe switches off two cancer-causing proteins 26 October 2015 | By Victoria White The discovery sheds new light on the role these proteins play in driving cancer cell proliferation...
Vertex and CRISPR Therapeutics to develop new treatments for genetic disease 26 October 2015 | By Victoria White The collaboration will evaluate the use of CRISPR-Cas9 across multiple diseases, including cystic fibrosis, where targets have been validated through human genetics...
ClearPath establishes Nosocomial Vaccine Corporation (NVC) 26 October 2015 | By Victoria White NVC has already initiated research collaborations with two partners to develop a nosocomial vaccine...
Study shows immunosuppressive effects of CA125 on farletuzumab 26 October 2015 | By Victoria White The new findings have led to the hypothesis that patients with high levels of CA125 have an immunosuppressive tumour microenvironment that may potentially enable cancer cells to escape immune-mediated cytotoxicity...
Celyad awarded US patent covering allogeneic human primary T-Cells 26 October 2015 | By Victoria White The US 9,181,527 Celyad Allogeneic Patent significantly strengthens Celyad’s patent portfolio in the CAR T-Cell field...
Disease recreated in mini-kidney organoids in the lab 23 October 2015 | By Victoria White The work paves the way for personalised drug discovery for kidney disease...
iPSC technology helps characterise healthy and diseased neurons 23 October 2015 | By Victoria White Using iPSC technology, researchers created 16 different cells lines, some using cells from healthy humans and others using cells from people with ALS or spinal muscular atrophy...
BanLec: the banana-derived antiviral agent 23 October 2015 | By Victoria White BanLec, a substance originally found in bananas and carefully edited by scientists, could someday fight off a wide range of viruses...
