Manipulation of primary cilia shows promise in osteoarthritis
28 October 2015 | By Victoria White
Scientists have demonstrated that medical manipulation of the primary cilia disrupts a key biological process called 'Hedgehog Signalling'...
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SRI International awarded $40m to develop contraceptive products
28 October 2015 | By Victoria White
Under the contract, SRI International will conduct all research and testing necessary to submit Investigational New Drug applications for promising drugs...
XBiotech to develop antibody against C. Difficile
27 October 2015 | By Victoria White
Using its proprietary True Human technology, the Company has begun screening human blood samples from donors to identify and clone a therapeutic antibody candidate...
Scientists discover a switch associated with epileptic seizures
27 October 2015 | By Victoria White
If the researchers blocked a central switch in epileptic mice, the frequency and severity of the seizures decreased...
Scientists build protein cage cancer drug delivery system
27 October 2015 | By Victoria White
Testing the system with lung cancer cells, the researchers showed that the ligand-guided protein cages selectively penetrated and killed more than 70% of the cancer cells...
Ipsen and EpiVax produce next generation botulinum toxins
27 October 2015 | By Victoria White
Their "stealth" botulinum neurotoxin programme capitalises on technological advances and promises to bring better drugs, with defined mechanisms of action...
Scientists discover switched off gene in prostate cancer cells
26 October 2015 | By Victoria White
The discovery could shed light on how prostate cancer spreads and provides a possible new target for the disease...
Chemical probe switches off two cancer-causing proteins
26 October 2015 | By Victoria White
The discovery sheds new light on the role these proteins play in driving cancer cell proliferation...
Vertex and CRISPR Therapeutics to develop new treatments for genetic disease
26 October 2015 | By Victoria White
The collaboration will evaluate the use of CRISPR-Cas9 across multiple diseases, including cystic fibrosis, where targets have been validated through human genetics...
ClearPath establishes Nosocomial Vaccine Corporation (NVC)
26 October 2015 | By Victoria White
NVC has already initiated research collaborations with two partners to develop a nosocomial vaccine...
Study shows immunosuppressive effects of CA125 on farletuzumab
26 October 2015 | By Victoria White
The new findings have led to the hypothesis that patients with high levels of CA125 have an immunosuppressive tumour microenvironment that may potentially enable cancer cells to escape immune-mediated cytotoxicity...
Celyad awarded US patent covering allogeneic human primary T-Cells
26 October 2015 | By Victoria White
The US 9,181,527 Celyad Allogeneic Patent significantly strengthens Celyad’s patent portfolio in the CAR T-Cell field...
Disease recreated in mini-kidney organoids in the lab
23 October 2015 | By Victoria White
The work paves the way for personalised drug discovery for kidney disease...
iPSC technology helps characterise healthy and diseased neurons
23 October 2015 | By Victoria White
Using iPSC technology, researchers created 16 different cells lines, some using cells from healthy humans and others using cells from people with ALS or spinal muscular atrophy...
BanLec: the banana-derived antiviral agent
23 October 2015 | By Victoria White
BanLec, a substance originally found in bananas and carefully edited by scientists, could someday fight off a wide range of viruses...
