New study looks at why pharma may prefer to invest in drugs over vaccines 3 March 2016 | By Victoria White According to the research, a drug for a disease that affects twice as many people will generate twice the revenue. But vaccine revenue depends on finer details about how the risk is distributed in the population...
ANGPTL4 inhibition linked to reduced risk of coronary artery disease 3 March 2016 | By Victoria White ANGPTL4 inhibits lipoprotein lipase (LPL), an enzyme that helps break down triglycerides, a form of fat derived from food...
Fighting Proteus mirabilis infections with viruses 3 March 2016 | By Victoria White Scientists at the University of Brighton have shown that bacteriophage can treat infections caused by Proteus mirabilis and prevent catheter blockage...
Researchers find Achilles’ heel of acute lymphoblastic leukaemia 2 March 2016 | By Victoria White Researchers have discovered that a GSK-J4 can kill acute lymphoblastic leukaemia that involves the TAL-1 gene...
Researchers investigate defects in the DJ1 gene in Parkinson’s 2 March 2016 | By Victoria White Researchers looked at the metabolism of neurons lacking DJ1 and discovered that two key metabolic pathways are affected...
Cypralis appoints a new Chief Scientific Officer 2 March 2016 | By Victoria White Cypralis, a company focussed on the discovery of novel therapeutics based on modulation of PPIases, has appointed Dr Michael Peel as Chief Scientific Officer...
Celyad gets patent for TCR-deficient CAR T-cell method 2 March 2016 | By Victoria White The US Patent 9,273,283 is the second patent of Celyad allogeneic intellectual property portfolio that is awarded by the USPTO...
UCI study points to new treatments to limit effects of Alzheimer’s 1 March 2016 | By Victoria White Using pexidartinib to flush away the inflammatory cells produced in reaction to beta-amyloid plaques, scientists restored memory function in test mice...
FDA makes $2 million available to fund natural history studies in rare diseases 1 March 2016 | By Victoria White The aim is to collect data on how specific rare diseases progress in individuals over time so that knowledge can inform and support product development and approval...
AChE peptide key driver for neuronal death in Alzheimer’s 1 March 2016 | By Victoria White The AChE peptide has been shown to drive production of both amyloid and hyperphosphorylated tau in Alzheimer's disease...
Electron microscopy details infection mechanisms of coronaviruses 29 February 2016 | By Victoria White High-resolution cryo-electron microscopy and supercomputing have now made it possible to analyse in detail the infection mechanisms of coronaviruses...
Lamellar teams up with ECFP to create novel Lamellasomes 29 February 2016 | By Victoria White Through the partnership, Lamellar hopes to gain a more detailed understanding of the biophysical properties of Lamellasomes and hence their mode of action...
PeptiMimesis to develop next generation therapeutic peptides 29 February 2016 | By Victoria White PeptiMimesis is a new biotech startup developing a novel class of therapeutic peptides using a breakthrough technology...
Tarantula toxin, ProTx-II, shows promise as a painkiller 29 February 2016 | By Victoria White ProTx-II, a peptide toxin found within the venom of the Peruvian green velvet tarantula, has a high potency and selectivity to inhibit the pain sensation receptor...
Regen completes preclinical experimentation for its NR2F6 checkpoint inhibitor 26 February 2016 | By Victoria White Regen has recently filed two patent applications covering the molecular pathways activated by NR2F6 silencing...