Microfluidic screening reveals SARS-CoV-2 antibody candidate 17 May 2021 | By Victoria Rees (Drug Target Review) Microfluidic screening technologies have been used to discover a promising antibody candidate against SARS-CoV-2 and the South African variant.
New mouse model could be used to develop better HIV treatments 17 May 2021 | By Victoria Rees (Drug Target Review) A new pre-clinical mouse model could enable the study of HIV infection and the testing of cell therapies against the virus.
Lipid droplets may prevent kidney damage from high-fat diets 17 May 2021 | By Victoria Rees (Drug Target Review) Researchers have shown in fruit flies that lipid droplets could prevent the kidney damage that leads to chronic kidney disease.
Protein associated with Lyme disease arthritis discovered 14 May 2021 | By Victoria Rees (Drug Target Review) A team has shown that the NapA protein, associated with Lyme disease, attracts inflammatory molecules in the body.
Natural killer cells and bispecific antibody target lymphoma tumours 14 May 2021 | By Victoria Rees (Drug Target Review) In pre-clinical studies, researchers showed that cord blood-derived natural killer cells and a bispecific antibody eliminated lymphoma cells.
Researchers reveal frameshifting as SARS-CoV-2 drug target 14 May 2021 | By Victoria Rees (Drug Target Review) A critical stage of the SARS-CoV-2 replication process, known as frameshifting, could be targeted by new drugs, researchers say.
Mitochondrial enzyme found to block ferroptosis, presenting cancer target 13 May 2021 | By Victoria Rees (Drug Target Review) The mitochondrial enzyme dihydroorotate dehydrogenase (DHODH) can block cell death, new research has shown, making it a cancer drug target.
Automated method to produce synthetic DNA created 13 May 2021 | By Victoria Rees (Drug Target Review) Researchers have developed a technique to synthetically produce DNA oligonucleotides that avoids the degradation of phosphoramidites.
New vaccine design developed to protect against Ebola virus 13 May 2021 | By Victoria Rees (Drug Target Review) Researchers have designed a new nanoparticle-based vaccine against Ebola that has shown promise in mice and rabbits.
Cell-based assays market set to exhibit CAGR of 8.5 percent 12 May 2021 | By Victoria Rees (Drug Target Review) The global cell-based assays market is expected to grow due to increasing investments into cell-based research and a rise in chronic diseases.
Scientists design new drug compound to combat malaria 12 May 2021 | By Victoria Rees (Drug Target Review) Researchers have developed a set of compounds designed to stop the malaria parasite being able to burst out of red blood cells and replicate.
Small molecule screens reveal new class of anticancer compounds 12 May 2021 | By Victoria Rees (Drug Target Review) Two screening techniques were used by researchers to find anticancer compounds that target the aryl hydrocarbon receptor.
Novel CRISPR strategy developed for Duchenne muscular dystrophy 12 May 2021 | By Victoria Rees (Drug Target Review) A CRISPR gene editing technique has been developed to restore dystrophin, which is missing in many Duchenne muscular dystrophy (DMD) patients.
New vaccine protects against COVID-19 and variants in pre-clinical studies 11 May 2021 | By Victoria Rees (Drug Target Review) A new vaccine has shown promise at protecting monkeys and mice from COVID-19, its variants and other coronaviruses.
Single-cell map of lung cancer sheds light on tumour development 11 May 2021 | By Victoria Rees (Drug Target Review) A spatial atlas of early-stage lung cancer has been compiled at single-cell resolution, revealing new therapeutic targets.
