gp120 protein shows promise in HIV vaccine design 30 October 2017 | By Dr Zara Kassam (Drug Target Review) Researchers have developed a vaccine candidate that spurs animals to produce antibodies against protective sugars of multiple HIV strains...
KSRP discovery gives a potential therapeutic target to combat trypanosomes 27 October 2017 | By Dr Zara Kassam (Drug Target Review) Researchers have discovered a new potential therapeutic target – located in the ribosome – to combat trypanosomes parasites...
Mature B lymphocytes accelerate the healing of acute and chronic wounds 27 October 2017 | By Dr Zara Kassam (Drug Target Review) Direct application of immune cells speeds and improves healing of acute and chronic wounds in animal models...
TP53 gene mutations may help catch ovarian cancer 27 October 2017 | By Dr Zara Kassam (Drug Target Review) Screening for tumour cells in the fallopian tubes may help detect the cancer years before it develops further...
NIH study identifies new targets for anti-malaria drugs 26 October 2017 | By Dr Zara Kassam (Drug Target Review) Researchers have sought to uncover the role of plasmepsins IX and X, produced by P. falciparum for metabolic processes...
CRISPR engineered to edit single RNA letters 26 October 2017 | By Dr Zara Kassam (Drug Target Review) New 'REPAIR' system edits RNA, rather than DNA, without permanently affecting the genome...
Declines in plasticity reveal promising targets for Alzheimer’s disease 26 October 2017 | By Dr Zara Kassam (Drug Target Review) Brain changes linked to memory loss may provide a new focus for exploring ways to treat or prevent dementia...
Fluorescent imaging with cetuximab safely used in glioblastoma patients 25 October 2017 | By Dr Zara Kassam (Drug Target Review) Antibody-based infrared fluorescent imaging can specifically distinguish cancer from normal tissue in patients with glioblastoma...
NOX4 mechanism identified as a culprit in kidney cancer evolution 25 October 2017 | By Dr Zara Kassam (Drug Target Review) Researchers have identified the molecular mechanism that causes kidney cancer to resist drug treatment...
APC protein affects immunity by preventing pre-cancerous inflammation 25 October 2017 | By Dr Zara Kassam (Drug Target Review) Mutations in the APC gene, harm the immune system, leaving it unable to tackle inflammation thereby favouring the development of cancer...
Asthma biomarkers identified from lung bacteria 24 October 2017 | By Dr Zara Kassam (Drug Target Review) New research suggests that the lung microbiome plays a significant role in asthma severity and response to treatment...
Self-regulating nanoparticles could treat cancer 24 October 2017 | By Dr Zara Kassam (Drug Target Review) Scientists have developed 'intelligent' nanoparticles which heat up to a temperature high enough to kill cancerous cells...
Five new malaria targets that could lead to an effective vaccine 23 October 2017 | By Dr Zara Kassam (Drug Target Review) Scientists have identified five targets that reduce the parasite's ability to invade red blood cells...
yTRAP used to quantitatively measure and manipulate protein aggregation 23 October 2017 | By Dr Zara Kassam (Drug Target Review) Researchers have built a synthetic genetic tool yTRAP to quantitatively sense, measure and manipulate protein aggregation in live cells...
Inhibiting β-lactamase may reverse antibiotic resistance 23 October 2017 | By Dr Zara Kassam (Drug Target Review) By developing a chemical to inhibit β-lactamase enzymes, a significant proportion of antibiotic resistance may successfully be reversed...
