New Alzheimer’s animal model more closely mimics human disease
Researchers have found that amyloid-? facilitates the interaction between the plaques and abnormal tau.
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DNA sequencing demonstrates use for treatment of chronic kidney disease
Results from a new study suggest that DNA sequencing could soon become part of the routine diagnostic examination for patients with chronic kidney disease.
GDF6 gene associated with metastatic melanoma
Researchers have revealed a protein active during early embryo development called GDF6 plays a primary role in metastatic melanoma...
Protein associated with ALS points to possible targets for therapeutic intervention
Scientists may have found possible targets for therapeutic interventions in the fight against Lou Gehrig’s disease.
Sperm RNA may serve as biomarkers of future health
Human sperm may hold the potential to serve as biomarkers of the future health of newborn infants, according to a new study.
DNA mutations shed in blood predicts response to immunotherapy
Blood sample, or liquid biopsy, can reveal which patients will respond to checkpoint inhibitor-based immunotherapies...
Stem cell-derived intestine model mimics innate immune responses
A stem cell-derived in vitro model displays key small intestine characteristics including innate immune responses.
Scientists visualise structure of key DNA repair component
The ATR protein has been imaged at ‘near-atomic resolution’, providing greater insight into its activation in DNA repair.
Tumour cell biology reveals characteristic that causes metastasis
A collaborative team of researchers in the US have uncovered characteristics of tumour cells that are linked to cancer metastasis.
Lung tumours communicate with bones to progress disease
Scientists at Massachusetts General Hospital (MGH) have identified how a type of lung cancer co-opts a portion of the immune system via bone marrow to increase tumour progression.
Scientists make key development in understanding type-2 diabetes mechanism
Scientists at the University of Geneva (UNIGE) have deciphered the mechanisms that link obesity with type-2 diabetes at the cellular level, thus explaining the reasons behind an association that is already well known.
Charles River announces success of integrated discovery project with ENYO Pharma
Capture compound mass spectrometry technology enables target identification...
Structure of primary optogenetic tool identified
Researchers have determined the 3-D structure of channelrhodopsin 2, a membrane protein widely used in optogenetics to control nerve cells with light...
The overlap of 3D bioprinting and 3D cell culturing in cancer research
SMi’s 3D Cell Culture conference will gather together a room full of CEOs, scientific pioneers and senior decision makers directly under one roof...
Inhibiting METTL3 destroys AML cells without harming normal blood cells
An unexpected drug target for acute myeloid leukaemia could open new avenues to develop effective treatments against the potentially lethal disease...
