IONIS-HTTRx lowers deadly Huntington’s disease protein
The first drug targeting the cause of Huntington’s disease was safe and well-tolerated in its first human trial…
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DTI technique predicts patients’ ability to fight the spread of cancer
A simple, non-invasive procedure that can indicate how long patients with cancer that has spread to the brain might survive and whether they are likely to respond to immunotherapy has been developed...
Chemists develop Washington Red dye for bio-imaging
Scientists have created an injectable dye that illuminates molecules with near-infrared light...
New research heralds future drug discovery pathways for hyperaldosteronism
A team of scientists in the United States has identified a mechanism that explains the development of hyperaldosteronism. These findings offer a potential path for drug discovery to treat the condition, which often leads to secondary hypertension.
How an incidental exhalation led to improved DNA detection device
While attempting to position two chips on a microscope, an involuntary exhalation by scientist Greg Madejski caused them to adhere to great effect.
Innovative probe visualises tumours
A new probe has the potential to help surgeons visualise primary non-fluorescing, low-grade gliomas during surgery to remove the tumour.
Novel compound restores immune response in patients with melanoma
A novel compound may restore immune response in patients with melanoma, according to a study presented at the ESMO Immuno Oncology Congress 2017.1
Scientists discover a small molecule that halts kidney disease progression
A team of researchers set out to discover the disease pathways of a rare genetic kidney disease and found a compound that stops the disease in its tracks.
Charles River adds ERS License to CRISPR/Cas9 service offering
Charles River Laboratories International, Inc. announced the expansion of its CRISPR/Cas9 service offering with the addition of a license from ERS Genomics Limited.
Healthy mitochondria may prevent Alzheimer’s disease
Scientists have provided a therapeutic approach to slow down the progression of neurodegeneration in Alzheimer's disease...
New weakness found in most common childhood malignant brain tumour
A new weakness found in medulloblastoma could lead to more personalised medicine and improved treatment for some patients.
FUNDC1 protein in cardiac muscle cells linked to heart failure
Reducing a protein found in the mitochondria of cardiac muscle cells initiates cardiac dysfunction and heart failure...
Pancreatic cancer: specific protein promotes development of pancreatitis and tumours
A study has shown that disruption to cell autophagy is involved in the development of pancreatic cancer.
UV light microscope proves useful diagnostic tool
Recent study shows how a microscope using ultraviolet (UV) light to illuminate samples enables pathologists to assess high-resolution images of biopsies and other fresh tissue samples for disease, quickly and effectively.
Anle138b blocks toxic ion flow linked to Alzheimer’s disease
A new small-molecule drug can restore brain function and memory in a mouse model of Alzheimer's disease by stopping toxic ion flow in the brain...
