Elimination of c-Raf kinase induces regression of advanced lung tumours 26 January 2018 | By Dr Zara Kassam (Drug Target Review) A study has shown how the elimination of the c-Raf kinase by genetic manipulation causes the regression of Kras oncogene-driven advanced lung tumours...
Statistical computing tool visualises employment trends in biomedical science 25 January 2018 | By Dr Zara Kassam (Drug Target Review) Scientists looking for jobs after completing their training may soon have a new tool that helps them evaluate various career paths...
MSK1 protein keeps metastatic breast cancer cells dormant 25 January 2018 | By Dr Zara Kassam (Drug Target Review) A study has identified the genes involved in the latent asymptomatic state of breast cancer metastases...
Systemic clearing of senescent astrocytes presents new therapeutic avenue for Parkinson’s disease 25 January 2018 | By Drug Target Review Researchers illuminate a new focal area for Parkinson’s disease therapy after demonstrating the beneficial effects of systemic clearing of senescent astrocytes.
Researchers uncover the origins of leprosy and reason for its drug resistance 25 January 2018 | By Drug Target Review Scientists in Switzerland have developed the tools to sequence genes from the leprosy bacterium, Mycobacterium leprae, revealing information about its origins and reasons behind its resistance to drugs.
Blocking 20-HETE chemical counters the siren call of aggressive cancers 24 January 2018 | By Drug Target Review Scientists have successfully blocked the powerful call of two types of aggressive cancer – glioblastoma and breast cancer – in laboratory models; with evidence that inhibiting the chemical 20-HETE halts tumour growth.
HIF-1 protein shows promise as a non-hormonal treatment for menorrhagia 24 January 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have identified a key protein that could explain why heavy bleeding occurs during menorrhagia, paving the way for potential treatments that avoid the need to take hormones...
Raman imaging technique shows Alzheimer’s disease progress in the brain 24 January 2018 | By Drug Target Review Using Raman optical technology, scientists can now produce images of brain tissue that is affected by Alzheimer’s disease...
Cryo-EM reveals critical OST complex and potential drug target 24 January 2018 | By Dr Zara Kassam (Drug Target Review) Scientists have revealed the atomic-level structure of a molecular complex responsible for modifying proteins, paving the way for the development of new medications...
Altered gut microbiome populations may cause blood infections in paediatric cancer patients 24 January 2018 | By Drug Target Review Scientists discover that altered gut microbiome populations appear to influence the onset of blood infections in paediatric cancer patients.
Corning to introduce new dissolvable microcarriers for improved large-scale cell expansion 24 January 2018 | By Corning Life Sciences Corning to unveil new product offerings at Cell & Gene Therapy World in Miami, Fla.
NIH to launch genome editing research program 24 January 2018 | By Dr Zara Kassam (Drug Target Review) Somatic Cell Genome Editing aims to develop tools for safe and effective genome editing in humans...
Energy storehouses in the brain may be source of Alzheimer’s 23 January 2018 | By Drug Target Review Research into the effects of Alzheimer’s disease on how mitochondria structures function has revealed that a highly toxic beta amyloid protein disrupts normal function.
Researchers create first stem cells using CRISPR genome activation 23 January 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have turned skin cells from mice into stem cells by activating Sox2 and Oct4 using CRISPR technology...
Computational method speeds hunt for new antibiotics 23 January 2018 | By Dr Zara Kassam (Drug Target Review) New algorithm reduces search time from hundreds of years to mere hours...
