Searching for targeted treatments for inflammatory diseases
Scientists have identified identified key regulators that are essential for controlling the inflammatory response in Crohn’s disease and multiple sclerosis.
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Old antibiotic compounds could become tomorrow’s life-saving drugs
Scientists and chemists are re-examining old compounds to see whether they could hold the key to a future drug to combat increasingly resistant bacteria...
Precise genetic cause of rare hypertension syndrome is discovered
Scientists at the Berlin Institute of Health have discovered how mutations in a new disease gene CLCN2 cause the unusual inherited form of high blood pressure: Familial hyperaldosteronism type II.
Reprogrammed brain cells exhibit symptoms of Huntington’s disease
Scientists have transformed skin cells from patients with Huntington's disease into the type of brain cell affected by the disorder...
CnAβ1 reduces cardiac hypertrophy and improves heart function
Scientists have identified a variant of the enzyme calcineurin, called CnAβ1, whose action reduces cardiac hypertrophy and improves heart function...
SMi’s 9th annual RNA Therapeutics conference will take place in just 2 weeks!
Presenting issues and real-life examples within the RNA space, SMi welcome insights and discussions into new technologies for single-stranded RNA, epigenetics to develop first-in class drugs in oncology, patenting RNA Therapeutics and exploring the latest developments in delivery systems, including Exosomes and Nanocomplexes. Read on for your exclusive discount to…
Charles River Laboratories makes investments in high-throughput screening infrastructure
Signs collaboration agreement with AstraZeneca to offer state-of-the-art technology to clients.
OTUD7A gene identified as key player in 15q13.3 microdeletion syndrome
Researchers have identified in a mouse model OTUD7A as the gene that accounts for many characteristics of 15q13.3 microdeletion syndrome...
Study uncovers therapeutic targets for aggressive triple-negative breast cancers
New findings have made inroads into a strategy to identify TNBC tumours at risk for metastasis...
Gene manipulation holds the key to personalised medicine
Researchers propose a novel approach to manipulate genes that may hold the key to the future of personalised medicine...
Chondroitin sulphate nets hold promise for heart failure treatments
Researchers discover molecular nets inside heart muscles which hold promise for new heart failure treatment...
Scientists uncover the secret to how piRNAs defend the genome
Researchers from the University of Chicago have uncovered the mechanism by which small RNA molecules (piRNAs) locate and silence foreign invading genes, whilst avoiding ‘self’ genes.
LiP-mass spectrometric analysis measures molecular interactions
Researchers have systematically analysed and quantified the interactions of all proteins with metabolites on the level of the whole proteome...
New to 2018: The role of artificial intelligence in drug discovery
SMi Reports: SMi’s 2nd annual Drug Discovery conference, taking place in London on 21 and 22 March 2018, will discuss the role of artificial intelligence in drug discovery.
PSMA PET/CT imaging provides precision radiation therapy for prostate cancer
A nuclear medicine scan may locate prostate cancer recurrence after radical prostatectomy early after disease recurrence and could help guide salvage radiotherapy...
