DNMT3A crystal structure linked to cancer development 12 February 2018 | By Drug Target Review Scientists offer important information for understanding de novo DNA methlylation...
PGEC-derived organoids produce stable gut and liver tissue 12 February 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have bioengineered organs that are free from the risk of tumour growth--and of sufficient volume and size for viable transplant...
Genomic sequencing augments diagnosis and treatment of lymphoid cancer 9 February 2018 | By Dr Zara Kassam (Drug Target Review) New assay may allow screening for 'actionable' gene mutations in routinely acquired archival biopsies...
PSMA PET/CT clearly differentiates prostate cancer from benign tissue 9 February 2018 | By Drug Target Review Using nuclear medicine, German researchers have found a way to accurately differentiate cancerous tissue from healthy tissue in prostate cancer patients.
Harnessing the power of genomic sequencing augments diagnosis and treatment of lymphoid cancer 9 February 2018 | By Drug Target Review A new study has established that hybrid-capture sequencing is the method of choice for sequencing “actionable” gene mutations across the most common forms of lymphoid cancer.
CpAM molecules advance fight against hepatitis B 9 February 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have made an important step forward in the design of drugs that fight the hepatitis B virus, which can cause liver failure and liver cancer...
Lab-grown eggs could pave way towards new fertility treatments 9 February 2018 | By Dr Zara Kassam (Drug Target Review) Human eggs have been fully grown in a laboratory, in a move that could lead to improved fertility treatments...
Scientists halt breast cancer spread 9 February 2018 | By Drug Target Review Scientists have discovered that the amino acid asparagine is essential for breast cancer spread, and by restricting it, cancer cells stopped invading other parts of the body in mice.
CRISPR method efficiently corrects DMD defect in heart tissue 8 February 2018 | By Dr Zara Kassam (Drug Target Review) Scientists have developed a CRISPR gene-editing technique that can potentially correct a majority of mutations that cause DMD...
New body of resistance gene research has potential to combat superbugs 8 February 2018 | By Drug Target Review Scientists in Denmark have made it possible to rank the risk of resistance genes and predict the evolution of existing and future drugs.
Scientists target glioma cancer stem cells which could improve patient survival 7 February 2018 | By Drug Target Review Dartmouth scientists have successfully uncovered a therapeutic approach that targets aggressive brain cancer stem cells and could lead to improved patient survival.
Nicotinamide riboside shows cognitive benefits in Alzheimer’s disease 7 February 2018 | By Dr Zara Kassam (Drug Target Review) A form of vitamin B3 has been found to prevent neurological damage and improve cognitive and physical function in a new mouse model of Alzheimer’s disease...
Study indicates holistic nature of Alzheimer’s disease (AD) progression 7 February 2018 | By Drug Target Review A collaboration of scientists in the United States has identified a distinct association between inflammation biomarkers in blood plasma and cerebrospinal fluid (CSF), and markers of Alzheimer’s disease (AD).
EMA discusses future Amsterdam premises 7 February 2018 | By Dr Zara Kassam (Drug Target Review) The EMA Management Board have met in an extraordinary session to discuss EMA’s future premises in Amsterdam...
Immune system found to protect against MRSA infections 7 February 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have discovered how the immune system might protect a person from recurrent bacterial skin infections caused by Staphylococcus aureus...