Experimental drug stops Parkinson’s disease progression in mice
Researchers say they have developed an experimental drug, similar to compounds used to treat diabetes, that slows the progression of Parkinson's disease...
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Algorithm used to map cancer resistance to drugs
New methods of studying the evolution of treatment resistance in head and neck cancer are being developed by researchers at the Johns Hopkins Kimmel Cancer Center...
Stem cells restore function in primate heart-failure study
Results suggest an approach that could be tested for treating people with heart failure...
Next-generation therapeutic helps immune cells detect, destroy cancer
Researchers have found that cancer cells evade destruction by macrophages in two ways...
CRISPR technology can correct Alpha-1 antitrypsin deficiency
Groundbreaking research demonstrates proof-of-concept for using CRISPR-Cas9 genome editing technology to correct the gene mutation responsible for AAT deficiency...
Novel drug therapy partially restores hearing in mice
A small-molecule drug is one of the first to preserve hearing in a mouse model of an inherited form of progressive human deafness, report investigators at the University of Iowa, Iowa City, and the National Institutes of Health’s National Institute on Deafness and Other Communication Disorders (NIDCD).
Administering hormones affects DNA
In an experiment with pigs, researchers have demonstrated for the first time that the administration of even extremely low doses of an endocrine disruptor - in this case, an endogenous oestrogen - leads to epigenetic changes in a pregnant sow’s DNA.
New cancer immunotherapy shows promise in early tests
Researchers report that in preclinical models they can amplify macrophage immune responses against cancer using a self-assembling supramolecule...
New biomarker provides personalised treatment options for bladder cancer
Researchers use data science and genomics to help determine best treatment options for specific bladder cancers...
Researchers apply computing power to track the spread of cancer
Researchers have developed a new computational method that increases the ability to track the spread of cancer cells from one part of the body to another...
C6 gene unlocks mysteries to our immunity
Researchers have identified a new gene that plays a critical role in regulating the body's immune response to infection and disease...
MicroRNA provides promise in search for simple, early test for Alzheimer’s
Researchers have found early evidence that tiny snippets of microRNA may help with early detection of conditions such as Alzheimer's disease...
Computational models provide genetic insight into atherosclerosis
Researchers find a gene in artery wall activated by lipids associated with coronary artery disease...
TRAF7 gene mutations associated with multisystem disorders
A team of researchers have identified four different mutations in the gene TRAF7...
Progress toward improved Wilson’s disease drug
Researchers have conducted promising preclinical experiments on a compound that could be used to treat Wilson's disease...
