Mouse models’ mimic lung disease
Researchers have finally been able to mimic IPF in mouse models - a debilitating disease, with no proper treatment and no cure...
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CRISPR technique skips over portions of genes that can cause disease
Researchers have adapted CRISPR to cause the cell's internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building...
Anticancer drug as an alternative to liver transplant
Mouse models showed promise when an anticancer drug was used to treat liver failure, resulting in liver regeneration and preventing liver related death...
Chemical that can kill glioblastoma cells identified
"As an experimental chemical, further rigorous testing and refinement of KHS101 is required before trials in people can begin.”
RUNX proteins essential for DNA repair
The research team identified that the more the DNA was damaged, the more RUNX proteins bound to DNA repair intermediaries...
New lead for Alzheimer’s research proposed
Researchers identified a connection between the way neurons handle iron and mutations that may cause inherited Alzheimer's disease...
Effective approach to optimising medicinal molecules
Computational methods accelerates and automates the process of optimisation of candidate molecules before performing preclinical trials...
IgG3 antibody can block B cells from fighting pathogens during HIV infection
Scientists have shown that in certain people living with HIV, a type of antibody called immunoglobulin G3 stops the immune system's B cells from doing their normal job of fighting pathogens...
Targeting the growth signals of ‘undruggable’ cancers
Dr Bivona and his team showed that the growth of multiple cancers slowed by suppressing the signalling pathway using an experimental compound...
Genetic model predicts risk for common deadly diseases
Using data collected from the UK, the data suggests that up to 25 million people in the US may be at more than triple the risk of coronary artery disease...
Combination therapy may be useful against resistant bacteria
The team found that colistin worked well with protein synthesis inhibitor antibiotics, which alone have no activity against Gram-negative bacteria...
Genetic tools uncover cause of early infantile epileptic encephalopathy
Researchers have developed high-tech tools to uncover the genetic cause of the most difficult to diagnose cases...
Injecting VIP into the eye improves corneal transplant survival
Results using mouse models suggest that vasoactive intestinal peptide may provide a new method of improving the outcomes of corneal transplant surgery...
Global NGS market report 2018-2024
The main areas identified to hinder NGS market growth are the lack of skilled professionals and complications relating to data storage...
Scientists counter epigenetic reprogramming for ischemic cardiomyopathy patients
Congestive heart failure is a terminal disease that affects nearly 6 million people in the U.S.; yet its management is limited to symptomatic treatments as its causal mechanisms – including its most common form, ischemic cardiomyopathy – are unknown.
