Gene differences that impact response to Cryptococcus identified 17 July 2019 | By Drug Target Review Using human data, a new study has examined how Cryptococcus genes impact patients with Cryptococcus Neoformans.
Chemical synthesis and biological screening combined on chip 16 July 2019 | By Victoria Rees (Drug Target Review) Researchers have developed a chip which facilitates and accelerates active substance production, characterisation and biological effectiveness.
New potential liver cancer treatment found with biomarker-guided strategy 16 July 2019 | By European Pharmaceutical Review A cellular pathway may reduce side effects and extend immunotherapy duration in patients with the most common form of liver cancer.
Study identifies protein key to successful chemotherapy 15 July 2019 | By Victoria Rees (Drug Target Review) A protein has been discovered as key for effective chemotherapy, meaning improved treatments for chemotherapy resistance can be developed.
Novel nanoparticles improve CRISPR gene editing 15 July 2019 | By Victoria Rees (Drug Target Review) A study has used new synthetic lipids to deliver CRISPR gene editing tools into cells with up to 90 percent efficiency.
Gene discovered to play key role in cancer metastasis 15 July 2019 | By Victoria Rees (Drug Target Review) A study has identified a gene key in the spread of cancer, which could point to improving treatments for the condition, say the researchers.
RNA editing capabilities expanded with new CRISPR platform 12 July 2019 | By Drug Target Review A research team have developed a new CRISPR platform called RESCUE (RNA Editing for Specific C to U Exchange).
Macrophages identified as cause of endometriotic pain 12 July 2019 | By Fraser Owen (Drug Target Review) Researchers have discovered that macrophages are a key cause for pain in women with endometriosis so could be a treatment target for the condition.
Vaccine strategy devised to boost T-cell therapy 12 July 2019 | By Drug Target Review A research team has developed a vaccine that advances anti-tumour T-cell populations and allows the cells to invade solid tumours.
Tauopathy-regulating protein identified 11 July 2019 | By Victoria Rees (Drug Target Review) Researchers have discovered that the VPS35 molecule can be utilised in preventing neurodegenerative disorders.
Role of protein in spread of cytomegalovirus discovered 11 July 2019 | By Victoria Rees (Drug Target Review) A study has revealed the role of a protein which enables human cytomegalovirus to spread, the number one cause of congenital birth defects in the world.
Inhibiting protein slows glioblastoma tumour growth 11 July 2019 | By Victoria Rees (Drug Target Review) Researchers have discovered that inhibiting the ID1 protein slows the growth of glioblastoma tumours and reduces resistance to chemotherapy.
New evidence shows cytotoxic T cells can destroy targets of large mass 10 July 2019 | By Drug Target Review New study shows the ability of CD8+ cytotoxic T cells to penetrate a large target, which opens avenues to destroy solid cancers.
New target identified for vestibular diseases 10 July 2019 | By Victoria Rees (Drug Target Review) Researchers have discovered a potential treatment for vestibular conditions such as dizziness in animal models.
‘Longevity gene’ could be replicated to fight cardiovascular disease 10 July 2019 | By Drug Target Review The so-called 'longevity gene' has been included in animal models, in which it stopped atherosclerosis.
