Gut microbiota in patients with sepsis linked to organ damage 30 August 2019 | By Rachael Harper (Drug Target Review) The gut microbiota has been linked to organ damage in patients with sepsis suggesting targeting intestinal microbiota may help patients' recovery.
Muscular dystrophy mutation shown to protect against HIV-1 29 August 2019 | By Victoria Rees (Drug Target Review) Researchers have discovered that a rare muscle disease causes resistance to HIV-1 infection in patients, providing insight into potential therapies.
Stem cell division in the geriatric brain blocked by signal 29 August 2019 | By Rachael Harper (Drug Target Review) It has been discovered that Id4 controls whether stem cells enter cell division and may be relevant for treating neurodegenerative disease.
Structure of crucial metabolic enzyme revealed by high-end microscopy 29 August 2019 | By Rachael Harper (Drug Target Review) Scientists reveal the atomic structure and regulative mechanism of the metabolic enzyme transhydrogenase.
Blocking kinase could provide treatment for prostate cancer 29 August 2019 | By Victoria Rees (Drug Target Review) Researchers have found that inhibiting a kinase in mice leads to the death of prostate cancer cells, providing a potential therapeutic target.
Study identifies molecule key in leukaemia treatment resistance 28 August 2019 | By Victoria Rees (Drug Target Review) Researchers have found a molecule, which when deleted, increases leukaemia sensitivity to natural killer cells and is a drug target.
Scientists develop retina-on-a-chip to study eye diseases 28 August 2019 | By Victoria Rees (Drug Target Review) Combining organoid and organ-on-a-chip technologies, researchers have created a model which will allow them to study eye diseases and treatments for the retina.
Blocking specific macrophages leads to tumour shrinkage 28 August 2019 | By Victoria Rees (Drug Target Review) A study has found that removing a particular kind of macrophage enables the immune system to attack tumours, providing a potential drug target.
Blocking new protein helps immune system to fight cancer 28 August 2019 | By Rachael Harper (Drug Target Review) A protein discovery could lead to a new and highly potent immune-therapeutic drug for the eradication of cancers using natural killer cells.
Possible treatment discovered for severe dengue disease 28 August 2019 | By Rachael Harper (Drug Target Review) New findings suggest a possible new treatment strategy for severe dengue disease using the tryptase inhibitor, nafamostat mesylate.
Telomere damage in cells is caused by runaway mitochondria 27 August 2019 | By Rachael Harper (Drug Target Review) Using new technology researchers have shown that sick mitochondria pollute the cells they are supposed to be supplying with power.
Novel bacteria gene activation method developed 27 August 2019 | By Victoria Rees (Drug Target Review) Researchers have created a new technique for activating genes using bacteria which could have therapeutic uses.
Unhealthy gut microbiomes in mice remodelled into more healthy ones 27 August 2019 | By Rachael Harper (Drug Target Review) Scientists have shown that there are molecules to remodel the gut microbiome and turn an unhealthful gut into a more healthful one for the first time.
Collaboration to discover MND treatments announced 27 August 2019 | By Victoria Rees (Drug Target Review) MSD and the Francis Crick Institute will work together on a project to identify disease targets for motor neuron disease.
Immune cell function in cancer immunotherapy revealed 27 August 2019 | By Victoria Rees (Drug Target Review) Researchers have discovered the roles that immune cells play in tumour growth and breast cancer immunotherapy which could aid in drug development.
