Researchers prevent schizophrenia progression in mice 10 September 2019 | By Victoria Rees (Drug Target Review) Using mice models in late adolescence, researchers have successfully treated schizophrenia which could help develop therapies for the condition.
Overcoming resistance in pancreatic cancer treatment 10 September 2019 | By Rachael Harper (Drug Target Review) Researchers have developed a new cocktail of drugs that shrink pancreatic tumours in mice by blocking pathways that cancer cells use.
Proteomic approach reveals metastatic melanoma resistance to therapies 10 September 2019 | By Victoria Rees (Drug Target Review) A study has used a proteomic method to uncover why some melanoma tumours do not respond to immunotherapy, which could improve treatments.
Researchers identify key mechanism of typhoid toxin 9 September 2019 | By Victoria Rees (Drug Target Review) The process of Salmonella typhi to damage DNA has been revealed by researchers at the University of Sheffield which could inform treatments.
Molecule discovered that regulates development of tumours 9 September 2019 | By Rachael Harper (Drug Target Review) Researchers discover that a non-coding region of the genome originates a key molecule for the proliferation of cancerous tumours.
HIV infant model opens new avenues for research 9 September 2019 | By Rachael Harper (Drug Target Review) An animal model to test HIV infection in infants could lead to biomarkers that predict viral rebound after ART interruption.
Compound promotes healing of myelin in nervous system disorders 6 September 2019 | By Rachael Harper (Drug Target Review) A compound that promotes the rebuilding of the protective sheath around nerve cells damaged in multiple sclerosis has been developed.
Tuberculosis mutation discovery could lead to better treatments 6 September 2019 | By Rachael Harper (Drug Target Review) New gene mutation discovery could lead to more rapid and effective therapies for tuberculosis.
Researchers develop new DNA microscopy technique 6 September 2019 | By Victoria Rees (Drug Target Review) The novel method for imaging molecules in cells and tissue samples, called DNA microscopy, could improve knowledge of disease development.
Medical Research Council updates brain tissue database 6 September 2019 | By Victoria Rees (Drug Target Review) The UK Brain Banks Network has been enhanced to include genomic data, which can be accessed by researchers worldwide.
Inhibiting kinase improves arrhythmogenic cardiomyopathy symptoms 5 September 2019 | By Victoria Rees (Drug Target Review) A research team has found that blocking a particular kinase in a mouse model of arrhythmogenic cardiomyopathy led to improved survival rates.
Researchers identify pancreatic cancer protein drug target 5 September 2019 | By Victoria Rees (Drug Target Review) A protein that causes pancreatic ductal adenocarcinoma has been identified as a therapeutic target by researchers.
AI learns chemistry language to predict how to make medicines 5 September 2019 | By Rachael Harper (Drug Target Review) An algorithm has been developed which can predict the outcomes of complex chemical reactions with over 90 percent accuracy which can be applied to drug development.
Uncharted area of genome mapped by advanced imaging 5 September 2019 | By Rachael Harper (Drug Target Review) Researchers have mapped a previously uncharted region of the human genome which could lead to tests for certain conditions in the future.
Streptococcal toxic shock syndrome vaccine candidate developed 4 September 2019 | By Victoria Rees (Drug Target Review) Researchers have created a vaccine to treat and prevent streptococcal toxic shock syndrome which showed success in mice models.
