AI can predict which research will translate to clinical trials 11 October 2019 | By Victoria Rees (Drug Target Review) Researchers have created an AI model that analyses the citations of studies, predicting their potential for eventual clinical application.
Bacterial strain identified that determines fate for rotavirus sufferers 10 October 2019 | By Drug Target Review Scientists in the US have identified a particular bacterial strain, Segmented filamentous bacteria (SFB), that can prevent and cure rotavirus in mice.
New therapeutic target identified for pulmonary fibrosis 10 October 2019 | By Rachael Harper (Drug Target Review) A genetic mutation that causes idiopathic pulmonary fibrosis has been identified and could lead to a new therapeutic approach to treating the disease.
Best targets for immunotherapy identified by new model 10 October 2019 | By Rachael Harper (Drug Target Review) A new algorithm has been developed which personalises which cancer mutations are best targets for immunotherapy.
Study reveals potential of gamma delta T cells to combat breast cancer 9 October 2019 | By Victoria Rees (Drug Target Review) Researchers have discovered that a specific subset of gamma delta T cells can be found in higher numbers of breast cancer survivor tissue, indicating its role in fighting the condition.
Alzheimer’s disease linked to tau-mediated RNA splicing errors 9 October 2019 | By Rachael Harper (Drug Target Review) A new study has shown the possibility of using RNA splicing as a potential molecular target for Alzheimer's disease.
Research reveals calcium signalling pathway in T cells 9 October 2019 | By Victoria Rees (Drug Target Review) A study has uncovered the mechanism behind calcium entry and exit into T cells, which could be used in development of autoimmune disease treatments.
Gene therapy for DMD safely preserves muscle function 8 October 2019 | By Rachael Harper (Drug Target Review) Gene therapy for the treatment of Duchenne muscular dystrophy has safely stopped the muscle deterioration associated with the disease.
New technology invented to streamline drug discovery 8 October 2019 | By Rachael Harper (Drug Target Review) New protein-painting technology could lead to developing cancer immunotherapy medicines that can be administered as a pill.
Sir Peter Ratcliffe awarded joint Nobel Prize for Physiology or Medicine 8 October 2019 | By Victoria Rees (Drug Target Review) The researcher Sir Peter Ratcliffe and two others have been jointly awarded the Nobel Prize for Physiology or Medicine 2019.
New compound keeps cells alive and functioning in a healthy state 7 October 2019 | By Rachael Harper (Drug Target Review) A world-first compound that can keep cells alive and functioning in a healthy state could be revolutionary for medical emergencies.
Researchers use new CRISPR method to alter specific bacteria strains 7 October 2019 | By Victoria Rees (Drug Target Review) A study has demonstrated how to use CRISPR to deliver DNA to particular bacteria, which could be used as an alternative to antibiotics.
Antibodies used to treat and reverse MS symptoms in mice 7 October 2019 | By Victoria Rees (Drug Target Review) Researchers have identified a protein on the surface of cells that cause MS and have used antibodies as an effective treatment for the condition in mice.
Protein receptor linked to cell death imaged for the first time 4 October 2019 | By Victoria Rees (Drug Target Review) Researchers have imaged an inflammation-related protein receptor on cell membranes which could inform future drug designs to prevent cell death.
Anticancer activity delivered by targeting mitochondrial cell regulator 4 October 2019 | By Rachael Harper (Drug Target Review) Disruption of the MFF-VDAC1 complex could lead to a potential therapeutic target for cancer.