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Scientists identify protein drug target to potentially treat cataracts

24 May 2021 | By Victoria Rees (Drug Target Review)

Researchers have shown that a protein named aquaporin can disrupt optical development, leading to cataract formation.

news

Genomic analysis reveals cellular cause of type 1 diabetes

20 May 2021 | By Victoria Rees (Drug Target Review)

Combining two genomic methodologies, researchers have shown that pancreatic exocrine cells are implicated in type 1 diabetes.

article

Millennia in the making: unlocking the medicinal value of CBD

20 May 2021 | By Dr Sotirios Karathanasis (Enveda Biosciences)

Dr Sotirios Karathanasis discusses the history of cannabis as a treatment and delves into the process of turning plant-based medicines into clinically proven drugs.

news

Potential COVID-19 antiviral formulated with siRNA-nanoparticles

19 May 2021 | By Victoria Rees (Drug Target Review)

Scientists have created an antiviral therapy using lipid nanoparticles that deliver siRNA to the lungs to treat COVID-19 in mice.

news

Novel inhibitor blocks myeloma cancer cell growth in mouse model

18 May 2021 | By Victoria Rees (Drug Target Review)

Having identified the histone demethylase KDM5A as a multiple myeloma target, researchers developed a KDM5 inhibitor to treat the cancer.

news

Asthma vaccine shows success in pre-clinical studies

18 May 2021 | By Victoria Rees (Drug Target Review)

A new conjugate vaccine has shown promise at protecting mice against the effects of cytokines associated with asthma.

news

Protein associated with Lyme disease arthritis discovered

14 May 2021 | By Victoria Rees (Drug Target Review)

A team has shown that the NapA protein, associated with Lyme disease, attracts inflammatory molecules in the body.

news

Natural killer cells and bispecific antibody target lymphoma tumours

14 May 2021 | By Victoria Rees (Drug Target Review)

In pre-clinical studies, researchers showed that cord blood-derived natural killer cells and a bispecific antibody eliminated lymphoma cells.

news

Researchers reveal frameshifting as SARS-CoV-2 drug target

14 May 2021 | By Victoria Rees (Drug Target Review)

A critical stage of the SARS-CoV-2 replication process, known as frameshifting, could be targeted by new drugs, researchers say.

whitepaper

Catalogue: Cytokines and growth factors from Sino Biological

13 May 2021 | By Sino Biological Inc.

Sino Biological has developed 1,000+ cytokines and receptors, including growth factors, cytokines, chemokines, interferons, interleukins, etc.

whitepaper

ebook: Accelerate vaccine development

13 May 2021 | By Molecular Devices

Our comprehensive portfolio suite is designed to optimize your productivity to get safe and efficacious vaccines and therapeutics to market faster.

news

Mitochondrial enzyme found to block ferroptosis, presenting cancer target

13 May 2021 | By Victoria Rees (Drug Target Review)

The mitochondrial enzyme dihydroorotate dehydrogenase (DHODH) can block cell death, new research has shown, making it a cancer drug target.

news

New vaccine design developed to protect against Ebola virus

13 May 2021 | By Victoria Rees (Drug Target Review)

Researchers have designed a new nanoparticle-based vaccine against Ebola that has shown promise in mice and rabbits.

news

Scientists design new drug compound to combat malaria

12 May 2021 | By Victoria Rees (Drug Target Review)

Researchers have developed a set of compounds designed to stop the malaria parasite being able to burst out of red blood cells and replicate.

news

Small molecule screens reveal new class of anticancer compounds

12 May 2021 | By Victoria Rees (Drug Target Review)

Two screening techniques were used by researchers to find anticancer compounds that target the aryl hydrocarbon receptor.

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