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Stem Cells

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iPSC-derived natural killer cells show promise against leukaemia in mice

16 June 2020 | By Victoria Rees (Drug Target Review)

By deleting the CISH gene from natural killer cells made from iPSCs, researchers say they have effectively treated leukaemia in vivo and in vitro.

video

Video: Overview of the KingFisher^TM instruments

10 June 2020 | By Thermo Fisher Scientific

ESHG 2019: Automated sample preparation using magnetic bead technology and KingFisher instruments.

video

Video: Isolate Circulating tumor cells using the KingFisher

9 June 2020 | By Thermo Fisher Scientfic

New opportunities for liquid biopsy: At automated workflow for isolating circulating tumor cells using KingFisher instruments.

article

Application of organoid technology for retinal disease modelling and drug discovery

4 June 2020 | By Valeria Chichagova (Newcastle University and Newcells Biotech)

The loss of retinal light-sensing photoreceptor cells is a leading cause of blindness and the number of individuals affected by retinal degenerative diseases is increasing with an ageing population. Currently, there are no treatments for these diseases and progress in finding new treatments is slow. This article explores the potential…

article

Using big data approaches to develop cell therapies

4 June 2020 | By Dr Owen Rackham (Duke-NUS Medical School)

An area where stem cell biology and medicine are combining effectively is the establishment of new cell therapies. However, current therapies are limited to a narrow set of cell types that can be isolated or created and expanded in vitro. Dr Owen Rackham discusses how utilising computational approaches will further…

whitepaper

Guide: Five ways biophysical tools help brain studies

3 June 2020 | By NanoTemper Technologies

Learn why researchers turned to biophysical methods to expose the molecular mechanisms of neurodegenerative diseases.

whitepaper

Application note: Monitoring of SMALP-nanodisc formation by microfluidic diffusional sizing

29 May 2020 | By Fluidic Analytics

Styrene–maleic acid (SMA) copolymers have become popular tools used in membraneprotein research as they can extract both lipids and membrane proteins from cellular membranes while preserving the bilayer structure of the membrane in so-called nanodiscs.

article

Stem Cells In-Depth Focus 2020

26 May 2020 | By Drug Target Review

The stem cells in-depth focus includes articles on using computational approaches to expand the applications of stem cell therapies and how organoids could be used to speed up the drug discovery process with a focus on retinal disease.

article

Drug Target Review – Issue 2 2020

26 May 2020 | By Drug Target Review

In this issue authors discuss the development of COVID-19 antibody therapies, how high-throughput screening enhances research at the Crick Institute and why combinations of immuno-oncology drugs could revolutionise treatment of advanced cancers. Also included in the issue are articles on stem cells and imaging.

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ebook: How to start your own lab

26 May 2020 | By NanoTemper Technologies

Learn practical tips from eight Principal Investigators about how to start your own lab.

news

Induced pluripotent stem cells and CRISPR reversed diabetes in mice

23 April 2020 | By Victoria Rees (Drug Target Review)

Induced pluripotent stem cells made to produce insulin and CRISPR, used to correct a genetic defect, cured Wolfram syndrome in mice.

news

Stem cells in COPD patient lungs revealed as drug target for condition

16 April 2020 | By Victoria Rees (Drug Target Review)

There are heightened levels of abnormal stem cells in the lungs of COPD patients, presenting a drug target that researchers are screening compounds against.

Mesenchymal stem cells as COVID-19 therapy

article

Mesenchymal stem cells secretome as a prospective therapeutic option for COVID-19 patients

13 April 2020 | By Avinash Kharat (Dr D Y Patil Vidyapeeth), Avinash Sanap ( Dr D Y Patil Vidyapeeth), Dr Ramesh Bhonde (Dr D Y Patil Vidyapeeth), Supriya Kheur (Dr D Y Patil Vidyapeeth)

Researchers propose using mesenchymal stem cells to counter the pro-inflammatory cytokines associated with COVID-19 coronavirus symptoms.

Skull with faded blue outline with a pink brain inside with large red spot

news

Transplanted reprogrammed skin cells repair stroke-damaged rat brains

9 April 2020 | By Hannah Balfour (Drug Target Review)

Skin cells reprogrammed into nerves and transplanted into the stroke-damaged rat brains formed functional connections that restored mobility and touch sensation.

video

Video: Increased reproducibility with KingFisher™ instruments

8 April 2020 | By Thermo Fisher Scientific

ESHG 2019 Conference Presentation: Using KingFisher™ to increase reproducibility in new applications using challenging samples.

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Stem Cells