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Nuclear tracer helps to study the aging brain
A PET nuclear tracer could help researchers to understand neurodegeneration in aging brains better, as it enters the brain and distributes quickly...
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Algorithm to more effectively identify antibiotic compounds
An international team of scientists has developed a candidate identification technique in the form of an algorithm that reduces the chances of rediscovering known compounds.
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Kidney disease biomarker could help detect COPD
A biomarker usually used with kidney disease, could potentially be used to detect COPD through identifying levels of albuminuria in urine...
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NIH to build cell atlas of the human body
The NIH's Common Fund programme looks towards building a cell map of all individual cells in the human body to aid the detection of disease...
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KCNB1 may be a root cause of Alzheimer’s disease
Researchers have identified that levels of the protein KCNB1 are increased in Alzheimer's brains, which may cause the increase of amyloid-beta plaques...
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Developments in EEG brain scans could detect mental disorders early
Researchers at the University of San Francisco have suggested how advances in EEG brain scanners could help to diagnose brain conditions earlier...
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New drug Metavert blocks growth of pancreatic cancer in mice
Scientists in California have discovered that a newly developed drug prevents pancreatic cancer in lab mice.
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Breast tissue simulations address enhanced MRI delays
Researchers address the delay of enhanced MRI cancer detection using simulations of women's breast tissue and higher MRI strengths...
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Application note: Miniaturisation of an HTRF methyltransferase assay that detects histone modifying activity
High throughput screening is mostly done in pharmaceutical companies that test whole libraries of compounds. Reducing the assay volume will reduce operating costs. At the same time it is necessary to prove that the smaller volume will not have a negative impact on assay sensitivity and reliability.
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Protein ‘trafficker’ provides insight into autism
The protein ASTN2 has been identified as a trafficking protein that ushers proteins away from the membrane ready for degradation in the cell...
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ELRIG UK Drug Discovery 2018 Event
ELRIG’s (European Laboratory Research & Innovation Group) Drug Discovery meeting, will take place at ExCeL, London, UK, located in the heart of the city, from 9 -10 October 2018...
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Lymphatic brain vessels represent potential avenue for MS treatment
Researchers in the U.S. have identified that lymphatic vessels in the brain appear to play a crucial role in the development and progression of multiple sclerosis (MS), providing focus for new treatment research.
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Application note: NanoBRETTM assay for monitoring of ligand binding to GPCRs in live cells, using the CLARIOstar® and the PHERAstar® FS
Due to the crucial role of G protein-coupled receptors (GPCRs) in mediating cellular responses to external stimuli, these receptors have been and will remain a prime focus for medical research and the pharmaceutical industry for many years to come. Their importance is especially highlighted by the statistic that 30-50% of…
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Testosterone replacement therapy could slow the progression of COPD
Researchers from Texas University have used data from men with COPD to ascertain that testosterone replacement therapy could be beneficial...
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Enhanced 3D neuron imaging could diagnose brain disease
Researchers have combined an open source software programme and commercially available hardware to image neuron activity at high resolution...
