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Change in neuron size could shed light on new treatments for ALS
Understanding how motor nerve cells respond to motor neurone disease could help researchers identify new treatment options...
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Pro72Arg gene variant increases tumour cell metabolism
Scientists have found a mechanism through which mutant p53 enhances metastasis by controlling tumour metabolism...
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Tempol provides a potential treatment for Chuvash polycythemia
A study in mice suggests that experimental drug may be effective against mountain sickness and other polycythemias...
news
Scientists discover critical molecular biomarkers of preeclampsia
Small non-coding RNAs may be used to devise a diagnostic blood test for pregnant women...
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HIC1 protein may protect against intestinal disease
Scientists find molecular link between Vitamin A derivative and mouse intestinal health...
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VILPs stimulate human cells to produce insulin-like hormones
In an unexpected finding, scientists have identified four viruses that can produce insulin-like hormones that are active on human cells...
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Osimertinib resistance explained by computer simulations
Scientists have used molecular simulations to understand the resistance to osimertinib - an anticancer drug used to treat types of lung cancer...
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Huntington’s disease provides new cancer weapon
Scientists have discovered why Huntington's is so toxic to cancer cells and harnessed it for a novel approach to treat cancer...
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Lab-grown eggs could pave way towards new fertility treatments
Human eggs have been fully grown in a laboratory, in a move that could lead to improved fertility treatments...
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Gene manipulation holds the key to personalised medicine
Researchers propose a novel approach to manipulate genes that may hold the key to the future of personalised medicine...
webinar
Streamlining drug discovery assays for cancer and cardiovascular disease
1 February 2018 | By PerkinElmer
This webinar discussed a screening assay that recapitulates the activation of ER stress sensor IRE1 and an assay to quantify cell migration phenotypes, as applied to cardiovascular target validation and drug discovery.
news
Alpha-4 beta-7 protein levels linked to HIV infection risk
Scientists have shown a relationship between the proportion of key immune cells that display high levels of alpha-4 beta-7 at the time of HIV infection and health outcomes...
news
Gimap5 gene mutations found to trigger immune diseases
Scientists discovered how a gene mutation affects T cell function to promote immune disorders...
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Mirror-image peptides of existing drugs provide longer-lasting therapeutic effects
Researchers have developed a new technology for creating more durable disease-fighting molecules which could lead to drugs with longer-lasting effects...
news
Sirt2 enzyme identified as therapeutic target for diabetes
Researchers have identified the sirtuin enzyme as a key player in regulating hepatic glucokinase through modifying GKRP, suggesting a potential therapeutic target for type 2 diabetes...
