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Parasitic worm study predicts potential drug targets and drugs

6 November 2018 | By Iqra Farooq (Drug Target Review)

The largest ever parasitic worm study has revealed nearly 1 million new genes, and has identified potential drug targets and drugs...

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Tethered antibodies may prevent influenza virus infections

6 November 2018 | By Drug Target Review

Investigational therapeutic candidate made with four antibodies tethered together shows promise against influenza A and B...

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Heat-resistant enzymes for cost-effective drugs

5 November 2018 | By Iqra Farooq (Drug Target Review)

The mechanisms and actions of heat-resistant enzymes are being investigated to aid better, more cost-effective drug design...

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Charles River to present collaborative methods at Neuroscience 2018

5 November 2018 | By Charles River Laboratories

Charles River Laboratories International, Inc. (NYSE: CRL) announced that its team of neuroscience drug discovery experts will present 26 scientific posters, both independently and collaboratively with clients, at Neuroscience 2018, the 48th annual meeting of the Society for Neuroscience (SfN)...

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Charles River and Distributed Bio enter exclusive partnership to create an integrated antibody discovery and development platform

5 November 2018 | By Charles River Laboratories

Charles River Laboratories International, Inc. announced that it has entered into an exclusive partnership with Distributed Bio, Inc., a leader in the computational design and optimisation of antibody discovery platforms...

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Image of serotonin activating its receptor for the first time

2 November 2018 | By Drug Target Review

Researchers have managed to image serotonin activating its receptor for the first time using the cutting edge technology, cryo-electron microscopy...

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MDM2 inhibitors as a possible treatment for uveitis

2 November 2018 | By Iqra Farooq (Drug Target Review)

MDM2 inhibitors could be used as a treatment for uveitis, a disease affecting the middle layer of the eye, causing inflammation and redness...

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Antibacterial compounds focusing on LsrK kinase

1 November 2018 | By Drug Target Review

Researchers at the University of Eastern Finland have developed antibacterial compounds based on the action of LsrK kinase...

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Water as a biomarker against cancer?

30 October 2018 | By Iqra Farooq (Drug Target Review)

The Tn antigen appears in around 90 percent of cancers, and its structure is greatly affected by the addition of water molecules...

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Perrottetinene from moss could be more medically beneficial than hemp

30 October 2018 | By Iqra Farooq (Drug Target Review)

Researchers have found that moss could be more medically beneficial than tetrahydrocannabinol (THC) which is being used illegally to treat various diseases...

news

Experimental vaccine could replace aspirin

29 October 2018 | By Drug Target Review

An experimental vaccine tested on mice could one day replace common blood thinners that are taken orally, such as aspirin...

news

Cyclic peptoids show promise as prostate cancer drug

25 October 2018 | By Drug Target Review

Scientists in the U.S. have developed molecules, termed cyclic peptoids, that block the action of genes that drive the growth of therapy-resistant prostate cancer, according to a new study.

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Atg2 tethers pre-autophagosomal membranes to endoplasmic reticulum

23 October 2018 | By Iqra Farooq (Drug Target Review)

Researchers at Tokyo University have investigated the role of the Atg2 protein in the process of autophagy to aid drug discovery into neurodegeneration...

news

Novel DNA vaccine offers broad protection against Influenza-A H3N

19 October 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers developed a novel DNA influenza vaccine based on four micro-consensus antigenic regions selected to represent the diversity of seasonal H3N2 viruses...

news

Rutin could be effective in treating snakebites from pit vipers

12 October 2018 | By Iqra Farooq (Drug Target Review)

The action of a venomous snakebite from vipers could be treated using a flavonoid called rutin, an inexpensive plant based compound...

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