List view / Grid view

Hit-to-Lead

news

Reversible antiplatelet therapy fights cancer metastasis and clotting

14 February 2019 | By Iqra Farooq (Drug Target Review)

A novel antiplatelet therapy could help to prevent heart attacks and stroke through preventing the formation of blood clots...

news

Protection against Mayaro virus using engineered DNA vaccine

8 February 2019 | By Drug Target Review

An engineered DNA vaccine that induces a robust and specific immune response against the disease, also provides complete protection...

article

Hit-to-lead discovery at a nonprofit research institute

7 February 2019 | By Anthony Pinkerton

Small molecule drug discovery has long been the domain of pharmaceutical companies, and that’s not likely to change anytime soon. But there’s a cadre of universities and nonprofit research institutes that have embraced drug development at its earliest stages, in some cases identifying and optimising compounds that target possible disease-driving…

news

Virtual drug discovery tackles unknown universe of drugs

7 February 2019 | By Drug Target Review

An online compound library consisting of the structure of over a billion molecules could be the future of drug discovery...

news

The path of metallodrugs in breast cancer cells

4 February 2019 | By Iqra Farooq (Drug Target Review)

The path a metallodrug uses to target and kill cancer cells could be used to design drugs to target triple-negative breast cancer...

news

Drug compound could be next-generation treatment for aggressive form of AML

29 January 2019 | By Drug Target Review

Researchers have developed a series of compounds that work not only on AML with common FLT3 mutation but also drug-resistant AML...

news

Chicken eggs containing human proteins could be key for future therapies

28 January 2019 | By Iqra Farooq (Drug Target Review)

Hens that lay human proteins in their eggs could offer hope for future therapies, especially with the simple, cost-effective system used...

news

Mavoglurant could improve eye gaze in fragile X patients

25 January 2019 | By Iqra Farooq (Drug Target Review)

A first stage trial involving the experimental drug mavoglurant has shown early success in the treatment of gaze avoidance in fragile X syndrome patients...

news

‘Hidden pocket’ could be targeted to treat strokes

21 January 2019 | By Iqra Farooq (Drug Target Review)

Researchers have identified a tiny hidden pocket on the NMDA receptor that could be targeted to treat strokes and seizures...

news

Nuclear tracers help assess new drugs for neurodegenerative diseases

21 January 2019 | By Dr Zara Kassam (Drug Target Review)

New nuclear medicine tracers could help medical researchers find a cure for Alzheimer's and other neurodegenerative diseases.

news

Naturally occurring potent antibiotic revealed

18 January 2019 | By Iqra Farooq (Drug Target Review)

A natural antibiotic was found to be made from an enzyme, through it triggering chemical reactions that help the production of the bacterial toxin...

news

Producing vaccines without the use of chemicals

15 January 2019 | By Drug Target Review

Innovative new technology will use electron beams to produce inactivated vaccines quickly, reproducibly and without the use of chemicals...

article

Small molecules could have big benefits in the battle against cancers

15 January 2019 | By Douglas J. Swirsky

Immunotherapy and targeted treatments, including targeted chemotherapy, continue to show great potential in cancer care. Future steps in their development will involve improving their ability to treat a wider range of cancers and a broader cross-section of the patient population, especially those for whom current treatments have shown limited efficacy...

news

Inhalable mRNA could treat lung disease

7 January 2019 | By Iqra Farooq (Drug Target Review)

An inhalable mix of a polymer and mRNA molecules, used to produce luciferase, could be the method of treating lung diseases in the future...

news

Triple-negative breast cancer could be treated using experimental treatment

4 January 2019 | By Drug Target Review

A mouse study has revealed that triple-negative breast cancer could be tackled by using recombinant Tinagl1 in therapy targeting signalling pathways...

Cookie	Type	Duration	Description
cookielawinfo-checkbox-advertising-targeting	persistent	1 year	The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Advertising & Targeting".
cookielawinfo-checkbox-analytics	persistent	1 year	This cookie is set by GDPR Cookie Consent WordPress Plugin. The cookie is used to remember the user consent for the cookies under the category "Analytics".
cookielawinfo-checkbox-necessary	persistent	1 year	This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Necessary".
cookielawinfo-checkbox-performance	persistent	1 year	This cookie is set by GDPR Cookie Consent WordPress Plugin. The cookie is used to remember the user consent for the cookies under the category "Performance".
PHPSESSID	session	1 year	This cookie is native to PHP applications. The cookie is used to store and identify a users' unique session ID for the purpose of managing user session on the website. The cookie is a session cookies and is deleted when all the browser windows are closed.
viewed_cookie_policy	persistent	1 year	The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data.
zmember_logged	session	1 year	This session cookie is served by our membership/subscription system and controls whether you are able to see content which is only available to logged in users.

Cookie	Type	Duration	Description
advanced_ads_browser_width	persistent	1 month	This cookie is set by Advanced Ads and measures the browser width.
advanced_ads_page_impressions	persistent	2 years	This cookie is set by Advanced Ads and measures the number of previous page impressions.
advanced_ads_pro_server_info	persistent	1 month	This cookie is set by Advanced Ads and sets geo-location, user role and user capabilities. It is used by cache busting in Advanced Ads Pro when the appropriate visitor conditions are used.
advanced_ads_pro_visitor_referrer	persistent	1 year	This cookie is set by Advanced Ads and sets the referrer URL.
bscookie	persistent	2 years	This cookie is a browser ID cookie set by LinkedIn share Buttons and ad tags.
IDE	persistent	2 years	This cookie is set by Google DoubleClick and stores information about how the user uses the website and any other advertisement before visiting the website. This is used to present users with ads that are relevant to them according to the user profile.
li_sugr	persistent	3 months	This cookie is set by LinkedIn and is used for tracking.
UserMatchHistory	persistent	1 month	This cookie is set by Linkedin and is used to track visitors on multiple websites, in order to present relevant advertisement based on the visitor's preferences.
VISITOR_INFO1_LIVE	persistent	5 months	This cookie is set by YouTube. Used to track the information of the embedded YouTube videos on a website.

Cookie	Type	Duration	Description
bcookie	persistent	2 years	This cookie is set by LinkedIn. The purpose of the cookie is to enable LinkedIn functionalities on the page.
GPS	persistent	30 minutes	This cookie is set by YouTube and registers a unique ID for tracking users based on their geographical location
lang	session	1 year	This cookie is set by LinkedIn and is used to store the language preferences of a user to serve up content in that stored language the next time user visit the website.
lidc	persistent	1 day	This cookie is set by LinkedIn and used for routing.
lissc	persistent	11 months	This cookie is set by LinkedIn share Buttons and ad tags.
vuid	persistent	2 years	We embed videos from our official Vimeo channel. When you press play, Vimeo will drop third party cookies to enable the video to play and to see how long a viewer has watched the video. This cookie does not track individuals.
wow.anonymousId	persistent	2 years	This cookie is set by Spotler and tracks an anonymous visitor ID.
wow.schedule	persistent	20 minutes	This cookie is set by Spotler and enables it to track the Load Balance Session Queue.
wow.session	persistent	20 minutes	This cookie is set by Spotler to track the Internet Information Services (IIS) session state.
wow.utmvalues	persistent	20 minutes	This cookie is set by Spotler and stores the UTM values for the session. UTM values are specific text strings that are appended to URLs that allow Communigator to track the URLs and the UTM values when they get clicked on.
_ga	persistent	2 years	This cookie is set by Google Analytics and is used to calculate visitor, session, campaign data and keep track of site usage for the site's analytics report. It stores information anonymously and assign a randomly generated number to identify unique visitors.
_gat	persistent	1 minute	This cookies is set by Google Universal Analytics to throttle the request rate to limit the collection of data on high traffic sites.
_gid	persistent	1 day	This cookie is set by Google Analytics and is used to store information of how visitors use a website and helps in creating an analytics report of how the website is doing. The data collected including the number visitors, the source where they have come from, and the pages visited in an anonymous form.

Cookie	Type	Duration	Description
cf_ob_info	persistent	1 minute	This cookie is set by Cloudflare content delivery network and, in conjunction with the cookie 'cf_use_ob', is used to determine whether it should continue serving “Always Online” until the cookie expires.
cf_use_ob	persistent	1 minute	This cookie is set by Cloudflare content delivery network and is used to determine whether it should continue serving “Always Online” until the cookie expires.
free_subscription_only	session	1 year	This session cookie is served by our membership/subscription system and controls which types of content you are able to access.
ls_smartpush	persistent	1 month	This cookie is set by Litespeed Server and allows the server to store settings to help improve performance of the site.
one_signal_sdk_db	persistent	Until cleared	This cookie is set by OneSignal push notifications and is used for storing user preferences in connection with their notification permission status.
YSC	session	1 year	This cookie is set by Youtube and is used to track the views of embedded videos.

Recommended

Hit-to-Lead