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New screening method identifies potential compounds to combat cancer
The new screening technique may enable development of novel combination-immunotherapy regimens against cancers and persistent infections.
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Novel peptide could lead to antibiotic for drug-resistant bacteria
A novel peptide has been discovered that attacks gram negative bacteria at a previously unknown site of action which presents a promising lead substance for the development of a new antibiotic.
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Video: Large-scale hiPSC-based drug development
From small-scale stem cell production to large-scale hiPSC-based drug development: The flexibility of stirred-tank bioreactors.
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Application note: Automated NGS library preparation on CyBio FeliX
The CyBio FeliX pipetting system was used to perform all liquid handling steps of the library preparation workflow for personal genome analysis.
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Application note: qPCR to Measure Minute Volumes in High Throughput
Improve the reproducibility of the real-time results in 384 well format with the application of a qPCR using a pipetting robot & standardized sample setup.
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Novel metabolic-focused high-throughput screening method developed
Researchers have created a new high-throughput screening system which could identify new drugs by focusing on nucleotide metabolism.
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Application note: Using SYPRO® Orange to Detect Protein Melting Temps
Investigation of thermal protein stability in high throughput using the application of thermal shift assay using SYPRO ® Orange in 96 well format.
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Application note: Detection of Mastitis Pathogens in Raw Milk
Detection of four pathogens of mastitis diseases using qTOWER³ in combination with extraction and detection systems for DNA diagnostics.
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Application note: Automated DNA Extraction and Species Analysis
Combining automated nucleic acid extraction, photometry and qPCR for easy-to-use and highly sensitive species analysis of cheese.
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Application note: Automated Extraction of High Molecular Weight DNA
SmartExtraction significantly simplifies the entire automated workflow of DNA extraction.
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Application note: Multiplex Fluorescent Western Blot Detection
Challenge: One touch imaging of multiple proteins on the same blot with NIR fluorescent tags. Solution? Automated imaging with the UVP ChemStudio.
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eBook: Simple as a Selfie: One-Button Scientific Imaging
Proper signal visualization, detection, and quantification are paramount to the acquisition of accurate and reproducible data...
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Potential treatment path shown for subtype of Charcot-Marie-Tooth disease
A new study could pave the way for developing a viable therapy for Charcot-Marie-Tooth patients affected by TyrRS mutations.
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Application note: In Vivo Imaging with GFP
Challenge: Non-invasive imaging of a patient-derived orthotropic mouse model of pancreatic cancer expressing GFP. The solution? In vivo imaging.
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eBook – Getting the Inside Story: In Vivo Imaging
In vivo imaging has been an indispensable and powerful tool in biomedical research, enabling a number of significant breakthrough discoveries.
