Professor Vicki Wysocki (Ohio State University)

article

Advances in mass spectrometry: unlocking the potential of chemical crosslinking as a structural biology tool

16 December 2019 | By Professor Albert JR Heck Utrecht (University and the Netherlands Proteomics Centre), Professor Alexander Makarov (Thermo Fisher Scientific), Professor Henning Urlaub (Göttingen University Medical Center), Professor Vicki Wysocki (Ohio State University)

Chemical crosslinking coupled with mass spectrometry (XL-MS) has been used for many years to study protein structure and function. However, recent advances in MS technology, as well as crosslinking reagents and data analysis tools, mean the technique has truly come of age. Here, Albert JR Heck, Alexander Makarov, Henning Urlaub…

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Professor Vicki Wysocki (Ohio State University)

Advances in mass spectrometry: unlocking the potential of chemical crosslinking as a structural biology tool