Professor Stylianos Michalakis (Ludwig Maximilian University)

article

Novel vectors for more efficient and less risky ocular gene therapy

22 June 2021 | By Professor Stylianos Michalakis (Ludwig Maximilian University)

Inherited blindness is the leading cause of vision loss in the working populations. Recently, the first gene therapy for the treatment of retinal dystrophy caused by mutations in the RPE65 gene became available. This gene therapy is based on adeno-associated virus (AAV) vectors injected under the retina. Subretinal injection is…

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Professor Stylianos Michalakis (Ludwig Maximilian University)

Novel vectors for more efficient and less risky ocular gene therapy