Douglas B. Kitchen (Albany Molecular Research Inc.)

article

Hit-to-lead in drug discovery

4 September 2016 | By Douglas B. Kitchen (Albany Molecular Research Inc.), Mark Wolf (Albany Molecular Research Inc.)

Starting in the 1970s, the drug discovery research process changed dramatically. Our understanding of biological targets and pathways grew and the largely empirical and target agnostic in vivo pharmacology approach was replaced with target-centric methods...

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Douglas B. Kitchen (Albany Molecular Research Inc.)

Hit-to-lead in drug discovery