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Bioassays and thin-layer chromatography has been used by scientists to analyse molecules in plant extracts as a fast and cost-effective method for identifying new drug compounds.
The National Drug Discovery Centre (NDDC) has opened in Australia, with support from the government to subsidise the screening of medicinal compounds.
A key receptor has been examined for the first time at high resolution which could lead to better treatments for conditions such as type 2 diabetes.
Scientists have created the first lab-dish models of the cellular clock, where each 'tick' stimulates the formation of the vertebra, which uses stem cells derived from adult human tissue.
A mechanism has been identified which regulates the release of insulin from β-cells and could be used to develop new treatments for type 2 diabetes.
A study has found a protein which, when depleted, resulted in Alzheimer’s disease symptoms appearing in mouse and brain tissue models.
A study has used CRISPR-Cas9 to treat obesity and type 2 diabetes symptoms in mice, highlighting the potential use in humans.
The protein FGFBP3 could be used in the future to reverse disorders associated with metabolic syndrome, such as type 2 diabetes and fatty liver disease...
Researchers in the states have discovered a particular gene mutation that slows down sugar metabolism in the gut, indicating future treatment options for individuals with cardiometabolic and sugar-associated diseases.
Researchers are hopeful of finding a means to inhibit obesity and its associated health problems after a study in which they blocked an RNA-silencing protein in the livers of mice, preventing obesity and diabetic conditions.
Using data collected from the UK, the data suggests that up to 25 million people in the US may be at more than triple the risk of coronary artery disease...
Scientists in Switzerland reveal the mechanisms behind the protective role of oestrogen against developing type 2 diabetes.
In an unexpected finding, scientists have identified four viruses that can produce insulin-like hormones that are active on human cells...
Researchers have identified the sirtuin enzyme as a key player in regulating hepatic glucokinase through modifying GKRP, suggesting a potential therapeutic target for type 2 diabetes...
Computational methods based on machine learning approaches are being introduced increasingly widely to screen the large number of molecules that have never participated in the drug discovery process, but which might have significant drug development potential. This article considers the latest advances in machine learning as applied to drug discovery...
