news Ground-breaking small molecule attenuates neuroinflammation in mice 27 September 2021 | By Anna Begley (Drug Target Review) Limiting neuroinflammation was shown to be a promising approach to treat neurological diseases such as stroke and spinal cord injury in mice.
news New synthetic biologic could treat obesity-related diseases 19 May 2021 | By Victoria Rees (Drug Target Review) A synthetically made glycopeptide biologic has shown promise as a treatment for obesity-related diseases in mice.
news Stem cell therapy repairs damage from dementia in mouse brains 22 April 2021 | By Victoria Rees (Drug Target Review) Researchers have developed a stem cell therapy that could treat the damage caused by dementia by launching a repair response.
news New mRNA delivery system effectively protects neurons in rats from ischemia 9 April 2021 | By Victoria Rees (Drug Target Review) Researchers have shown that an mRNA delivery system can be used to produce the BDNF protein in rats to protect neurons from ischemia.
news Team modifies therapeutic molecule to improve stroke treatment 19 February 2021 | By Victoria Rees (Drug Target Review) Researchers have shown that adding a polymer to glutamate-oxaloacetate transaminase means the molecule can treat stroke for up to six days in rats.
news Severe symptoms of COVID-19 are caused by brain infection in mice, finds study 20 January 2021 | By Hannah Balfour (Drug Target Review) Researchers found that SARS-CoV-2 persists in the brain after it is cleared in the lungs and concluded the severest and longest lasting symptoms of COVID-19 may be caused by brain infection.
news Researchers develop new potential stroke treatment 4 January 2021 | By Victoria Rees (Drug Target Review) A team has shown that synthetic molecule LAU-0901 plus aspirin-triggered NPD1 can repair brain damage in an experimental model of stroke.
news Researchers discover how SARS-CoV-2 reaches the brain 1 December 2020 | By Hannah Balfour (Drug Target Review) A new study has identified the mechanisms through which the SARS-CoV-2 virus enters the brain and how the immune system responds once it does.
news ‘Neuroregenerative’ study uses glial cells for stroke repair in primates 16 November 2020 | By Victoria Rees (Drug Target Review) In rhesus macaques, a team were able to induce neural regeneration from brain internal glial cells, repairing damage from stroke.
news Autoantibodies and over-active neutrophils may be cause of COVID-19 blood clots 3 November 2020 | By Hannah Balfour (Drug Target Review) According to a new study, blood clots in patients with severe COVID-19 are caused by an autoimmune antibody that circulates in the blood and attacks cells.
news New class of inhibitors protect mice from neurodegeneration 9 October 2020 | By Victoria Rees (Drug Target Review) So called "interface inhibitors" could be used to protect against neurodegeneration, researchers have said.
news Researchers develop potential drug to prevent heart attacks 23 July 2020 | By Victoria Rees (Drug Target Review) A novel drug has been created which prevented the blood clotting associated with heart attacks and strokes in pre-clinical studies.
news Neurological complications of COVID-19 8 July 2020 | By Hannah Balfour (Drug Target Review) Researchers report COVID-19 can cause a range of severe neurological symptoms, which may be the main presentation of COVID-19 in some patients.
news Antisense oligonucleotide treatment cures Parkinson’s disease in mice 25 June 2020 | By Victoria Rees (Drug Target Review) By administering a one-time PTB antisense oligonucleotide therapy to mice, researchers observed an increase in neurons and elimination of Parkinson's from the models.
news Transplanted reprogrammed skin cells repair stroke-damaged rat brains 9 April 2020 | By Hannah Balfour (Drug Target Review) Skin cells reprogrammed into nerves and transplanted into the stroke-damaged rat brains formed functional connections that restored mobility and touch sensation.
