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Non-opioid based target identified to potentially treat chronic pain

27 May 2021 | By Victoria Rees (Drug Target Review)

Researchers have discovered that blocking TRPC5 activity treated chronic pain in mouse models of various conditions.

Preclinical candidate CGRP antagonist selected for advancement as potential migraine treatment

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Preclinical candidate CGRP antagonist has potential as treatment for migraines

18 May 2017 | By Sarah Wills (Drug Target Review)

A preclinical candidate calcitonin gene-related peptide (CGRP) antagonist has been nominated for advancement into further preclinical studies as an investigational treatment for migraine.

news

Lilly announces $1m grant for the American Migraine Foundation

10 June 2016 | By Victoria White, Digital Content Producer

The grant will be used to build a registry that will contain clinical data to advance the research and discovery of new treatments for migraine...

news

Vagus nerve stimulation shown to suppress CSDs – a trigger for migraine

12 January 2016 | By Victoria White

Cortical spreading depressions (CSDs) are believed to be responsible for the aura, or visual disturbance, that frequently precedes some migraines, and have been a significant target for pharmaceutical development...

news

Teva and Heptares to develop treatments for migraine

25 November 2015 | By Victoria White

The companies have entered an agreement to discover and develop novel, small-molecule CGRP antagonists for the treatment of migraine...

news

Key US patents granted for GPCR-focused drug discovery platform arising from pioneering research and translational expertise at MRC and MRC Technology

17 December 2014 | By MRC Technology

Structure-based drug discovery platform targets challenging GPCRs linked to human disease...

news

Teva completes acquisition of Labrys

21 July 2014 | By Teva

...opens door to a strong and novel migraine prevention and treatment franchise within its CNS portfolio.

news

Teva to acquire Labrys Biologics, Inc.: Novel migraine prophylaxis treatment adds significant new dimension to Teva’s growing pain care franchise

4 June 2014 | By Teva

Teva Pharmaceutical Industries Ltd., and Labrys Biologics, Inc., announced that Teva has entered into a definitive agreement to acquire Labrys, broadening Teva’s array of biotechnology assets and capabilities...

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