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£280 million donated for COVID-19 research in three months
A study has shown that the COVID-19 pandemic has resulted in a high level of research donations, making the condition the third most funded disease on average by year.
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Malaria
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Cervical cancer cell-killing molecule manzamine A found in Indonesian sponge
A study has revealed that a sponge endemic to an Indonesian bay produces manzamine A, a compound which inhibits proteins in cervical cancers.
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Novel assay designed to aid malaria drug and vaccine development
Researchers have developed a novel affordable and reproducible assay to study the malaria parasite, using a new cytoplasmic dye, Cell Trace Far-Red (CTFR).
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Novel compound to kill malaria parasites developed by researchers
A collaborative team has developed a compound called WM382, which targets two crucial enzymes in the malaria parasite, effectively killing it.
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Tobacco mosaic virus creates novel malaria vaccine candidate
Researchers in the United States have used particles from the tobacco mosaic virus (TMV) to produce a new much-needed malaria vaccine.
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New capillary model could provide new therapies for malaria
Researchers have produced a capillary model which allows investigation of the dynamics of blood flow obstruction in real scale and could be used to test new therapies for P. falciparum malaria.
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Rhomboid protease role observed using dynamic imaging
Researchers have been able to watch rhomboid proteases in a native lipid environment which may be useful for the development of Parkinson's and malaria medication.
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Protective antibodies identified that could be key to malaria vaccine
A new study has identified antibodies that may hold the key to creating the first effective vaccine against malaria infection in the blood.
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Study reveals potential for malaria prevention vaccine
Researchers have identified a novel drug target for the prevention of malaria.
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Genomic approach to studying widespread malaria
Researchers have suggested that the most widespread human malaria parasite could be studied and possibly treated using genomics...
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Scientists image antibodies working together against malaria
Cryo-EM was used to image the antibodies attaching to the circumsporozoite protein, which is the most abundant protein on the surface of malaria...
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Nonresponsive NK cells directly impact malaria severity
The failure of natural killer cells (NK cells) to respond to infection explains why malaria causes a worse reaction in some patients than others.
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Promising new vaccine developed for vivax malaria
A study indicates the possibility of using tiny vesicles derived from human immature red blood cell as a vaccine platform...
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Six compounds identified from 70,000 to help eradicate malaria
Researchers from Imperial College London have identified 6 compounds from almost 70,000 that could help to eradicate malaria...
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Computational analysis identifies a new clinical phenotype of severe malaria
Researchers have applied a computational analysis based on networks in order to identify biologically relevant phenotypes apart from those currently defined by the WHO...
