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inflammation

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CARD8 protein could be novel atherosclerosis drug target

27 November 2020 | By Hannah Balfour (Drug Target Review)

Researchers demonstrate that the CARD8 protein plays a key role in regulating the inflammation that causes atherosclerosis and other inflammatory diseases.

cells in blue and green on a dark background

news

Cellular senescence as a drug target

27 October 2020 | By Hannah Balfour (Drug Target Review)

New research reveals that age-related declines in cellular function and proliferation occur in multiple stages, accompanied by different inflammatory responses.

man with hand over heart with cutaway of a blood vessel with a blood clot

news

Novel antiplatelet drug is effective at treating heart attacks in mice, say researchers

16 July 2020 | By Hannah Balfour (Drug Target Review)

The novel nanoparticle delivered Mp6 peptide was able to inhibit thrombosis and reduce inflammation without increasing the risk of bleeding in mice after heart attacks.

Potential of widely used drug could be unlocked with new method

news

New mass spec technique used to determine structure of sugars

25 March 2020 | By Rachael Harper (Drug Target Review)

A new method has been invented that boosts the mapping of heparan sulfates and which the researchers say could be widely used for drug discovery.

news

Previously unknown role of dendritic cells in inflammation revealed

13 December 2019 | By Victoria Rees (Drug Target Review)

A study has demonstrated that dendritic cells play a key role in inflammation and how TNF inhibitors can prevent them from fighting infections.

news

Inflammatory regulatory protein identified by researchers

22 November 2019 | By Victoria Rees (Drug Target Review)

A study has discovered that the PKM2 protein plays a role in regulating immune cells and blocking this could be a potential treatment for inflammatory diseases.

news

Protein receptor linked to cell death imaged for the first time

4 October 2019 | By Victoria Rees (Drug Target Review)

Researchers have imaged an inflammation-related protein receptor on cell membranes which could inform future drug designs to prevent cell death.

news

Study presents new ways of developing chronic inflammation treatment

2 September 2019 | By Rachael Harper (Drug Target Review)

Researchers have found a new way to treat the inflammation involved in chronic diseases.

news

Study identifies novel lupus drug target

3 June 2019 | By Victoria Rees (Drug Target Review)

Structure of internal regulator molecule identified, presenting lupus drug potential.

news

Tissue-damaging protein channel identified

21 May 2019 | By Victoria Rees (Drug Target Review)

Researchers have discovered an acid-activated protein which could stop damage to tissues as a result of stroke and other health issues.

news

Diagnostic technique reveals biomarker differentiating bladder cancer from inflammation

12 February 2019 | By Drug Target Review

A biomarker that can differentiate between chronic cystitis (inflammation of the bladder) and a non-muscle invasive-type blood cancer could aid diagnosis...

news

Inhibiting inflammation by blocking release of TNF alpha

16 November 2018 | By Drug Target Review

Researchers at Karolinska Institutet collaborated with other researchers to develop a compound that prevents inflammation by blocking release of TNF alpha...

news

Anti-inflammatory bacterial protein discovered in zebrafish

8 November 2018 | By Iqra Farooq (Drug Target Review)

An anti-inflammatory bacterial protein discovered in zebrafish could lead to the discovery of anti-inflammatory proteins within humans...

news

Perrottetinene from moss could be more medically beneficial than hemp

30 October 2018 | By Iqra Farooq (Drug Target Review)

Researchers have found that moss could be more medically beneficial than tetrahydrocannabinol (THC) which is being used illegally to treat various diseases...

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inflammation