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Covid-19

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Computational modelling reveals SARS-CoV-2 mutation ‘hotspots’

20 May 2021 | By Victoria Rees (Drug Target Review)

A new modelling method could be used as a surveillance tool to monitor emerging infectious SARS-CoV-2 variants, scientists say.

news

Potential COVID-19 antiviral formulated with siRNA-nanoparticles

19 May 2021 | By Victoria Rees (Drug Target Review)

Scientists have created an antiviral therapy using lipid nanoparticles that deliver siRNA to the lungs to treat COVID-19 in mice.

news

Microfluidic screening reveals SARS-CoV-2 antibody candidate

17 May 2021 | By Victoria Rees (Drug Target Review)

Microfluidic screening technologies have been used to discover a promising antibody candidate against SARS-CoV-2 and the South African variant.

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Researchers reveal frameshifting as SARS-CoV-2 drug target

14 May 2021 | By Victoria Rees (Drug Target Review)

A critical stage of the SARS-CoV-2 replication process, known as frameshifting, could be targeted by new drugs, researchers say.

news

Automated method to produce synthetic DNA created

13 May 2021 | By Victoria Rees (Drug Target Review)

Researchers have developed a technique to synthetically produce DNA oligonucleotides that avoids the degradation of phosphoramidites.

news

New vaccine protects against COVID-19 and variants in pre-clinical studies

11 May 2021 | By Victoria Rees (Drug Target Review)

A new vaccine has shown promise at protecting monkeys and mice from COVID-19, its variants and other coronaviruses.

news

Second mechanism of action discovered for COVID-19 drug remdesivir

11 May 2021 | By Victoria Rees (Drug Target Review)

Researchers have found that a metabolite of remdesivir potentially targets a SARS-CoV-2 protein involved in suppressing the host cell's defence response.

article

Healthcare demands drive domestic UK biotech investment

11 May 2021 | By Dmytro Spilka (Solvid)

Dmytro Spilka explains why UK biotech companies are receiving increasing levels of investment and why this trend is likely to continue.

article

Airway-on-a-chip technology enables COVID-19 drug repurposing

7 May 2021 | By Victoria Rees (Drug Target Review)

An airway-on-a-chip has been used to show that amodiaquine inhibits SARS-CoV-2 infection, making it a potential COVID-19 therapeutic.

news

Computational epitope map of SARS-CoV-2 Spike protein developed

7 May 2021 | By Victoria Rees (Drug Target Review)

Researchers have produced a computational simulation of the SARS-CoV-2 Spike protein, finding spots that glycans do not cover.

news

UK Government funds facility to test vaccines against COVID-19 variants

5 May 2021 | By Victoria Rees (Drug Target Review)

The UK Government will invest £29.3 million to test the effectiveness of COVID-19 vaccines against variants in 3,000 blood samples a week.

news

Antibodies cover entirety of SARS-CoV-2 Spike protein, study shows

5 May 2021 | By Victoria Rees (Drug Target Review)

Researchers have found that over 80 percent of antibodies target sections of the SARS-CoV-2 Spike protein other than the RBD.

news

New 3D lung-on-a-chip model enables study of respiratory diseases

4 May 2021 | By Victoria Rees (Drug Target Review)

Scientists have developed a 3D lung-on-a-chip model of the distal lung and alveolar structures, enabling the study of COVID-19.

news

UK to host summit with CEPI to accelerate vaccine development

3 May 2021 | By Victoria Rees (Drug Target Review)

A summit will be held between the UK and CEPI to raise funds for vaccine research and development in a bid to avert future pandemics.

news

UK Government to fund £37 million into genomics projects

30 April 2021 | By Victoria Rees (Drug Target Review)

UK Health Secretary Matt Hancock has announced £37 million of funding for genomics and data projects to support the life sciences sector.

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