news
Using anti-malaria drugs to slow tumour growth
Anti-malaria drugs, called chloroquines, target PPT1 from cancer cells, with researchers identifying how the drugs eliminate tumour growth in cancers...
List view / Grid view
Cancer
news
Defective damage repair to DNA results in chromosome chaos
German researchers have shown how defective damage repair to DNA results in chromothripsis - clustered chromosomal rearrangements...
news
CRISPR used to prevent cancers tied to EBV and KSHV
Researchers have discovered a possible path forward in preventing the development of cancers tied to two viruses, including the virus that causes infectious mononucleosis...
news
Scientists test new anti-PD-L1 cancer vaccine against melanoma
An experimental cancer vaccine that boosts the immune system's ability to fight cancers could work in tandem with other cancer therapies to fight aggressive tumours, scientists have reported...
news
Scientists pinpoint mechanism by which mutant p53 protein promotes cancer
Scientists in Australia have discovered how the most important gene in preventing cancer, TP53, is hampered in its tumour-fighting efforts by mutant p53 proteins.
news
Droplet Digital PCR detects and quantifies cancer mutation
Two ddPCR-based assays were developed to detect the two mutations in the promoter region of the TERT gene, which could be used as biomarkers...
news
Water as a biomarker against cancer?
The Tn antigen appears in around 90 percent of cancers, and its structure is greatly affected by the addition of water molecules...
news
Protein sequencing method could transform biological research
A team of researchers have demonstrated a new way to sequence proteins that are much more sensitive than existing technology, identifying individual protein molecules rather than requiring millions of molecules at a time
news
Atg2 tethers pre-autophagosomal membranes to endoplasmic reticulum
Researchers at Tokyo University have investigated the role of the Atg2 protein in the process of autophagy to aid drug discovery into neurodegeneration...
news
Single molecule fluorosequencing to transform biological research
Single molecule fluorosequencing could revolutionise the way researchers analyse disease, with the method enabling the investigation of single cells...
news
Critical cancer immunity genes identified using genetic barcoding
Genetic barcoding using Pro-codes and CRISPR could be used to identify critical cancer immunity genes to aid future therapeutics...
news
Protein mTOR regulated by Src in cancer growth
Researchers at Baylor College of Medicine and Texas Children's Hospital have identified a connection between cancer proteins mTORC1 and Src...
news
RNA circuits making gene therapy more effective
Circuits consisting of single-stranded RNA have been shown to be make gene therapy more effective, and allows precise control over the therapy...
news
Cancer stem cells use normal genes in abnormal ways
Researchers have identified that MHC Class I-high, CDK1 high molecules may be at the heart of conditions including melanoma, pancreatic and colon cancers...
news
Elrig 2018: Drug discovery using small and large molecules
The Drug Target Review team are at Elrig Drug Discovery 2018 in the London ExCel...
