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What is new in the world of imaging?
In this article, Drug Target Review’s Hannah Balfour discusses three of the latest developments in imaging for disease research and drug development.
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bacterial infection
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Novel compounds show efficacy against C. diff
Researchers have developed two novel trifluoromethylthio compounds which showed potent activity in protecting mice from Clostridioides difficile (C. diff) infection.
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Book mechanism identified as communication method for bacterial toxins
Researchers have identified the mechanism by which highly toxic compounds communicate, and how they use vesicles to be transported...
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Simple mechanism that ensures bacterial resistance
The team used techniques used by physicists along with highly specialised equipment to investigate deep into the bacterial membrane...
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Disrupting quinolones to prevent antibiotic resistance
Disrupting the communication between bacteria and quinolone signalling can inhibit the the production of toxins and virulence factors...
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Combination therapy may be useful against resistant bacteria
The team found that colistin worked well with protein synthesis inhibitor antibiotics, which alone have no activity against Gram-negative bacteria...
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Bacterial outer membranes may be key to new antibiotics
The outer membrane surrounding the cell wall of bacteria may be a key target for approaches to a new form of antibacterial drugs...
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PET tracer identifies bacterial infections
The new imaging agent offers a non-invasive method of detecting infection and monitoring antibiotic therapy...
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Bodies’ natural defence against bacteria discovered at Lund
Researchers in dermatology at Lund University in Sweden believe they have cracked the mystery of why our bodies can quickly prevent an infection from spreading uncontrollably during wounding. They believe this knowledge may be significant in developing new ways to counteract bacteria.
