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Expert view: The path to the high-hanging fruit: access to greater diversity and rapid down-selection

Posted: 24 March 2020 | | No comments yet

Therapeutic monoclonal antibodies are proven and effective treatment options but many of the ‘low-hanging fruit’ therapeutics have already been identified.

As we turn to more difficult targets, such as G-protein coupled receptors (GPCRs) and ion channels, two capabilities are crucial for success: access to greater antibody diversity and the ability to rapidly identify functional lead candidates. The Opto Plasma B Discovery 2.0 Workflow addresses both of these needs by providing access to broad B cell diversity and rapid down-selection of leads in an automated workflow run on the Beacon® platform.

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