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Imaging In-Depth Focus 2019

Posted: 6 June 2019 | | No comments yet

In this in-depth focus, the challenges of imaging are explored including how to develop high-resolution images. Also discussed are new imaging technologies to aid drug discovery.

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    Included in this In-Depth Focus:

    • High-content imaging: challenges of the 3D world
      The potential of three-dimensional cell culture models is now well-recognised by scientists, however there are some challenges. Margaritha Mysior and Jeremy Simpson address some of the common challenges of working with spheroids and organoid models — including how they are developed and how to obtain high-resolution, high-content images and how to develop three-dimensional high-resolution imaging assays.
    • Image-based characterisation of cancer biotherapeutics
      Siobhán Leonard, Victoria Juskaite, Laura Murch from LifeArc, an independent medical research charity in the UK, explain how they’re using the latest imaging technologies to progress drug discovery campaigns and identify the most promising candidates for antibody-based therapies.