List view / Grid view
28 May 2021 | By Victoria Rees (Drug Target Review)
Scientists have shown that trapped LC3B protein in brain cells enables Parkinson's disease to spread, presenting a drug target.
14 September 2020 | By Victoria Rees (Drug Target Review)
Scientists have found two active substances that allowed cells to reactivate the production of a protein that prevents the onset of Parkinson's disease.
25 June 2020 | By Victoria Rees (Drug Target Review)
By administering a one-time PTB antisense oligonucleotide therapy to mice, researchers observed an increase in neurons and elimination of Parkinson's from the models.
28 January 2020 | By Hannah Balfour (Drug Target Review)
Research identified a small molecule that targets the mRNA of α-synuclein and prevents the formation of the protein, an approach which could provide novel neurodegeneration therapies.
20 November 2019 | By Rachael Harper (Drug Target Review)
Molecular drivers of Parkinson's disease have been revealed by scientists who also determined how they impact the functions of genes involved in the condition and the results may point to potential new treatments.
21 January 2019 | By Dr Zara Kassam (Drug Target Review)
Researchers have investigated the ability of gut microbiota to influence the bioavailability of levodopa, a drug used in the treatment of Parkinson's...
14 November 2018 | By Drug Target Review
A team of neurologists have found that one reason Lewy bodies develop is that a molecule, USP13, has removed all the "tags" placed on alpha-synuclein that mark the protein for destruction...
21 July 2018 | By Dr Zara Kassam (Drug Target Review)
Researchers identify Parkinson's disease as a possible autoimmune disease...
6 July 2018 | By Dr Zara Kassam (Drug Target Review)
Study raises doubts on a previous theory of Parkinson’s disease...
5 July 2018 | By Dr Zara Kassam (Drug Target Review)
Researchers say they have developed an experimental drug, similar to compounds used to treat diabetes, that slows the progression of Parkinson's disease...
23 May 2018 | By Dr Zara Kassam (Drug Target Review)
The mechanism our immune cells use to clear bacterial infections like tuberculosis might also be implicated in Parkinson's disease...
30 April 2018 | By Dr Zara Kassam (Drug Target Review)
A collaborative team of researchers has found that elevated levels of certain types of lipids in the brain may be an early sign of Parkinson's...
5 January 2018 | By Dr Zara Kassam (Drug Target Review)
Researchers have found that patients with Parkinson's disease have more errors in the mitochondrial DNA within the brainstem, leading to increased cell death...
21 November 2017 | By Charles River Laboratories
Are selective, brain-penetrant inhibitors of LRRK2 an answer?
14 September 2017 | By Dr Zara Kassam (Drug Target Review)
Researchers have identified the first case of a patient with Parkinson's disease carrying a mutation in the ACMSD gene...
